Effects of a next-generation neurotrophic compound in a toxin model of Parkinson’s disease
Objective: Investigate the effects of a peripherally administered novel neurotrophic compound, CMx01a, in 6-hydroxydopamine rat model of Parkinson’s disease. Background: Neurotrophic factors are promising drug…Brain 5-HT1 receptor binding in multiple system atrophy: A [18F]-MPPF PET study
Objective: The primary objective was to compare brain 5-HT1a receptor binding between patients with multiple system atrophy (MSA) and healthy controls (HC). The secondary objectives…Glucocerebrosidase activity and atypical parkinsonism: a multi-centre exploratory study
Objective: We aimed to determine the frequency of Glucocerebrosidase (GBA) deficiency (subclinical Gaucher's Disease type 1, GD1) in patients with atypical parkinsonism (AP) with features…Key neuropathological features separating corticobasal degeneration from other related disorders
Objective: This study investigated the key neuropathological features that could separate corticobasal degeneration (CBD) from related parkinsonian disorders by using a decision tree algorithm. Background:…Staircase sign for Atypical and Secondary parkinsonism
Objective: The aim of this study was to investigate the difference in the preference of staircase climbing in PD and atypical/ secondary parkinsonism when they…Benign Infantile Tremor Syndrome (BITS): a new movement disorder
Objective: We present infants at our institution presented with action tremor with onset weeks to months later after birth and otherwise similar to neonatal jitteriness. Background: Several benign movement disorders in infancy have been described including…Simultaneous, levodopa-responsive Holmes’ tremor and hemiparkinsonism due to midbrain cavernous malformation
Objective: We report a case of concomitant Holmes’ tremor (HT) and hemiparkinsonism (HP) attributable to a single structural lesion with robust clinical response to levodopa.…A tailored and multifactorial fall prevention program for people with Parkinson’s disease: a feasibility study
Objective: To determine the feasibility and acceptability of a fall prevention program for people with moderate to severe Parkinson’s disease (PD). Background: Evidence shows exercise…Managing Functional Movement Disorder in Outpatient Physical Therapy: A Case Report of Belly-Dancer Dyskinesia
Objective: Abdominal dyskinesia, often referenced as belly dancer syndrome, is a poorly understood clinical presentation involving involuntary, undulating movements of the abdomen.1 Few cases have…Validation of previous empirical studies on the effect of Argentine Tango on the geriatric population with and without neurodegenerative disease
Objective: To objectively validate empirical studies regarding the effect of Argentine Tango (tango) on individuals with Parkinson’s disease (PD) and within the general geriatric population,…
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