Healthcare resource utilisation and costs among patients with versus without Huntington’s disease in the US population
Objective: Compare the marginal healthcare resource utilisation (HRU) and costs between US patients with Huntington’s disease (HD) and non-HD controls. Background: HD is a genetic,…A longitudinal PET study to assess the state of microglia activation in a Phase 2 study of Laquinimod as a treatment for Huntington’s disease (LEGATO-HD)
Objective: To assess in vivo in Huntington’s disease (HD) changes in microglia activation state, due to treatment with laquinimod, as reflected by changes in 11C-PBR28…White matter abnormalities and its relation to cognitive impairment in isolated Rapid Eye Movement sleep behavior disorder
Objective: To study white matter (WM) abnormalities and global cortical atrophy in isolated rapid eye movement sleep behavior disorder (IRBD) patients and its relation to cognitive…The relationship between MIBG myocardial scintigraphy and clinical factors in multiple system atrophy
Objective: This study aimed to clarified the relationship between the degree of MIBG accumulation and clinical factors in patients with MSA. Background: 123I-MIBG myocardial scintigraphy considered to…Pregnancy Outcomes Following Exposure to OnabotulinumtoxinA Update – 29 Years of Safety Observation
Objective: The present study evaluated pregnancy outcomes following onabotulinumtoxinA exposure to provide a cumulative 29-year safety update. Background: A previous publication of pregnancy outcomes in…Visuomotor reaction time can predict IQ in children
Objective: This study investigated whether visuomotor reaction time in 5 year-old children predicts intelligence test scores in 8 year-old children using the longitudinal approach. Background:…Dendritic cells and brain metabolites in Tourette’s
Objective: We aimed to study in vivo aspects of neuro-inflammation in Tourette syndrome (TS) patients exploring frequency and distribution of circulating blood-derived dendritic cells and…Evaluation of Proactive and Integrated Management and Empowerment in Parkinson’s Disease (PRIME Parkinson) in The Netherlands a prospective observational study
Objective: We will evaluate the utility of PRIME Parkinson care on a single primary endpoint (parkinsonism-related complications), which reflects the Population Health dimension, and on…Serum Neurofilament light chain levels and disability milestones in Lewy body diseases
Objective: To evaluate the relationship between motor, cognitive and autonomic symptoms and serum Neurofilament light chain levels in Lewy bodies disorders, namely Parkinson' s disease…Cognitive Fatigue from Attention Cognitive Load in Parkinson’s Disease
Objective: To determine cognitive fatigue in Parkinson’s disease (PD) patients after attention demanding task and stress and to investigate predictors of cognitive fatigue. Background: Fatigue…
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