Caspr2 antibody associated spinal myoclonus
Objective: We report two patients with spinal myoclonus and Contactin-associated protein-2 (Caspr-2)-antibodies, idiopathic in one and paraneoplastic in the other. Background: Caspr-2-antibodies have classically been…Large-Scale Network Changes in the Pathophysiology of Essential Tremor
Objective: To assess functional brain network architecture in participants with medically-refractory essential tremor (ET) and to correlate the strength of these networks with clinical tremor…Differential Diagnosis Between Functional Facial Spasm and Hemifacial Spasm: Role of Blink Reflex
Objective: We aimed to test the value of Blink Reflex (BR) as an electrophysiological tool in differentiating functional facial spasm (F-FS) from hemifacial spasm (HFS).…Cost-Utility Analysis of Flexible Intervals with IncobotulinumtoxinA Versus Fixed Dosing with OnabotulinumtoxinA in the Management of Cervical Dystonia and Blepharospasm in Major Canadian Markets
Objective: The aim was to carry out a cost-utility analysis for IncobotulinumtoxinA (INCO) administered with flexible treatment intervals compared to onabotulinumtoxinA (ONA) administered with fixed…On Time, Every Time: The Effect of Cohort Ward Triage, Specialist Nursing & Admission Pre-Alert on Parkinson’s Medication Management
Objective: To explore whether implementing dedicated cohort warding, specialist nursing and acute admission pre-alert improves the medication management of patients with Parkinson’s (PwP). Background: Previous…Are oromotor deficits a late stage signs in Parkinson’s disease?
Objective: To assess any preclinical signs of dysphagia in early PD. Background: Pre-clinical stages of Parkinson’s disease (PD) include the subtle signs of autonomic dysfunction,…Relationship Between a-syn RT-QuIC and a-syn Neuropathologic Burden in Dementia with Lewy Bodies
Objective: To determine if measures of alpha-synuclein (a-syn) real time quaking induced conversion (RT-QuIC) activity are related to a-syn neuropathologic burden in dementia with Lewy…Exploring cognitive aspect of linguistic prosody in Parkinson’s disease
Objective: To explore the correlation between linguistic prosody and cognition in Parkinson's disease Background: Around 90% of patients with Parkinson’s disease (PD) report speech deficit.…Modifiable Comorbidities Associated with Rate of Cognitive Decline in Parkinson’s Disease
Objective: To determine the association between baseline modifiable comorbidities, including cardiovascular disease risk factors, mood disorders, and sleep characteristics, and the rate of change in…Both Symptomatic and Asymptomatic Orthostatic Hypotension is Associated with Cognitive Decline Over Time in Parkinson’s Disease
Objective: To compare cognitive changes over time between Parkinson's disease (PD) patients with orthostatic hypotension (OH) and without OH, and between those with symptomatic OH…
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