Identification and characterization of anti-prionic compounds that disassemble Tau prions as a novel therapeutic approach for tauopathies
Objective: Stabilization of monomeric Tau protein by transient and high-affinity binding ligands is a novel and highly innovative anti-prionic treatment strategy for tauopathies. Background: Tauopathies…Robotic Assisted Arm Training in Parkinson’s disease rehabilitation: A pilot study
Objective: The aim and objective of this study was to evaluate whether robotic assisted arm training might improve upper limb function in patients with Parkinson’s…Understanding characteristics, healthcare resource use and costs of patients with Parkinson’s disease prior to and after diagnosis of cognitive impairment
Objective: The primary goal of this retrospective cohort study was to understand characteristics, healthcare resource use (HCRU) and costs of patients with PD before and…Pareidolias and Cognition in Isolated REM Sleep Behavior Disorder
Objective: The objective of this study is to investigate the relationship between errors on the pareidolia test and global cognition in patients with REM sleep…Influence of emotion-affective apathy in theory of mind in Parkinson’s disease patients
Objective: The study aimed to investigate apathy subdomains (reward deficiency syndrome, emotional distress, executive function, auto-activation deficit) and cognitive executive functions differences between PD patients…Information processing components in Parkinson’s disease with and without impulse control disorders: identification of diagnostic and predisposition markers
Objective: To search for differences in specific components of cognitive processing in Parkinson’s disease (PD) patients with and without impulse control disorders (ICD) in order…Candidate plasma miRNAs and EV protein as novel biomarkers in Parkinson’s disease patients with cognitive impairment and dementia
Objective: To determine the diagnostic value of circulating miRNAs and the extracellular vesicle proteins for early detection of patients with Parkinson’s disease and mild cognitive…Cortical pathology in Glucocerebrosidase mutation carriers with anxiety: An MRI study
Objective: To employ Magnetic Resonance Imaging (MRI) and investigate structural pathology in the cortex of Glucocerebrosidase (GBA) gene mutation carriers. Background: Mutations in the GBA…Genetic risk scores and hallucinations in Parkinson’s disease patients
Objective: To examine the overlap of genetic architecture for Alzheimer’s disease (AD), schizophrenia (SZ), and PD with the genetic architecture for the occurrence of hallucinations…Variants in the saposin D domain of prosaposin gene are linked to Parkinson’s disease
Objective: To investigate whether the variants of prosaposin can be linked to Parkinson's disease (PD) [1]. Background: Recent growing investigations have promoted the evidence of…
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