Non-motor Symptoms after Treatment with Levodopa-Carbidopa Intestinal Gel in Patients with Advanced Parkinson’s Disease: Analysis of the COSMOS Observational Study
Objective: Examine non-motor symptoms in patients with advanced Parkinson’s disease (APD) in a real-world clinical setting following ≥12 months of treatment with levodopa-carbidopa intestinal gel…The Clinical Heterogeneity of Orthostatic Hypotension in PD Patients
Objective: The objects of the research were to investigate the clinical heterogeneity of orthostatic hypotension(OH) in PD Patients, to explore the possible risk factors for…Apathy as a non-motor symptom(NMS) in patients with Parkinson’s disease(PwPD) and patients with Huntington’s disease(PwHD) in Tomsk, Russia
Objective: The aim is to evaluate and compare the apathy profile in PwHD and PwPD, using the same clinical criteria to assess the severity of…RBD and autonomic dysfunction in newly diagnosed Parkinson’s disease patients
Objective: To determine whether newly diagnosed Parkinson’s disease (PD) patients with REM sleep behavior disorder (RBD) are more likely to have symptoms of autonomic dysfunction.…Unmet psychological needs of People with Parkinson’s disease
Objective: To investigate whether Parkinson’s disease (PD) specialists are identifying patients with Parkinson’s psychological needs and referring them to appropriate services. Background: A number of…Age-dependent expression of α-synuclein and its modification in non-neurodegenerative intestinal tract
Objective: To investigate the feasibility of α-synuclein(α-Syn) pathology in enteric nervous system (ENS) as a diagnostic marker for Parkinson's disease, and to clarify the distribution…A longitudinal study on alpha-synuclein in plasma neuronal exosomes as a biomarker for Parkinson’s disease development and progression
Objective: This study explored the potential use of alpha-synuclein (α-syn) in plasma neuronal exosomes as a biomarker for early Parkinson’s disease (PD) diagnosis and disease…Anxiety in Parkinson’s disease is associated with changes in the brain fear circuit
Objective: The aim of this study was to identify the anatomical and functional changes related to anxiety, especially in the “fear circuit”, by comparing PD…Attitudes of Care Partners Toward Medications for Parkinson’s Disease Psychosis
Objective: To explore attitudes regarding use of medications among care partners of individuals with Parkinson’s disease psychosis. Background: Parkinson’s disease (PD) psychosis is a highly…Donepezil for mild cognitive impairment in Parkinson’s disease: A 48-week follow-up study
Objective: To investigate the efficacy of donepezil for mild cognitive impairment (MCI) in Parkinson’s disease (PD). Background: MCI is common in PD. The mechanism of…
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