Motor and cognitive symptoms in parkinsonism are associated with loss of long-range white matter fibers: Structural network changes in Vascular Parkinsonism and Parkinson’s disease
Objective: This study seeks to identify structural brain circuitry changes that may help to explain the appearance and severity of parkinsonism symptoms in clinical cohorts…Impaired Structural Connectivity in Parkinson’s Disease and its Neuropsychological Correlates
Objective: The aim of this study was to detect disrupted structural connectivity in Parkinson's disease (PD) patients classified according to their cognitive status, with and…Inertial-sensor based full-body kinematics reveals an unstable gait with increased variability in patients with evidence of dopaminergic denervation with 123I-FP-CIT SPECT
Objective: Distinguish patients with and without dopaminergic denervation (as assessed by 123I-FP-CIT-SPECT – DaTscan) with Inertial-sensor full body kinematics (FBK) assessment. Background: The differential diagnosis…Retinal Pathology in Parkinson’s Disease: A Longitudinal Study with Optical Coherence Tomography
Objective: The aim of this study was to find retinal pathology in Parkinson’s disease (PD) via Optical Coherence Tomography (OCT) that deteriorates over time, as…Levodopa Changes Functional Connectivity Patterns in Subregions of the Primary Motor Cortex in Patients with Parkinson’s Disease
Objective: To investigated functional connectivity pattern changes in M1 subregions and relationships to improved clinical symptoms following levodopa administration. Background: The primary motor cortex (M1)…Prefrontal cortical activity and the control of walking in people with freezing of gait
Objective: To investigate the influence of freezing of gait (FoG) on automaticity of walking in people with Parkinson’s disease (PD). Background: A hallmark of healthy…A reliable measure of rigidity with a novel robotic device
Objective: The objective of our study was to objectively measure the rigidity in PD patients, using a recently validated robotic device. Background: Rigidity is one…Bilateral double beta peaks in a PD patient with STN electrodes
Objective: We aimed to record LFPs of the subthalamic nucleus (STN) from a PD patient with a new implantable pulse generator (IPG), which is capable…Impulse Control Behaviours in People with Parkinson’s Disease: Findings from the Parkinson’s Disease Real-World Impact Assessment (PRISM) Study
Objective: Presence of impulse control behaviour (ICB) was assessed in PRISM, a European survey of people with Parkinson’s disease (PwP) and their care-partners. Background: Impulse…Orthostatic hypotension in Parkinson’s disease
Objective: We aimed to identify whether orthostatic hypotension (OH) is a prodromal marker of Parkinson’s disease (PD) or a symptom of later disease. Background: Many…
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