Diagnostic Demography of the Ataxia Unit at UNIFESP: 12 years experience
Objective: To describe the historical demography of diagnosed ataxia cases made in a tertiary neurological outpatient clinic in Sao Paulo, Brazil. Background: The term ataxia…Disconnected brain in functional movement disorders with anxious & depressive symptoms
Objective: The aim of this study was to investigate the functional brain network abnormalities underlying depression and/or anxiety symptoms (DEP/ANX) in functional movement disorders (FMD).…First Scientific Description of the Hepato-Lenticular Degeneration
Objective: Hepato-Lenticular Degeneration (HLD) first described by German pathologist Friedrich Theodor von Frerichs in 1854, but in the West it called Wilson's Disease. In Russia…VMAT 2 inhibitor and Antipsychotic use in Individuals with Huntington’s Disease
Objective: To retrospectively investigate whether the concomitant use of VMAT2 inhibitors and antipsychotics in individuals with Huntington's disease (HD) is associated with an increased occurrence…Translatable biomarkers in gene therapy for Huntington’s Disease: learnings from pre-clinical studies
Objective: We have developed AAV5-miHTT, a recombinant AAV-based gene therapy expressing an engineered microRNA that specifically binds to HTT exon1, resulting in lowering of both…Progression of cortical thinning and neuropsychological decline in isolated Rapid Eye Movement sleep behavior disorder
Objective: We aimed to investigate the progression over time of cortical thickness and cognitive functions in isolated REM-sleep behaviour disorder (IRBD) compared to healthy controls (HC).…hUC-MSCs ameliorated CUMS-induced depression by modulating complement C3 signaling-mediated microglial polarization during astrocyte-microglia crosstalk
Objective: To demonstrate whether hUC-MSCs can benefit depressive-like behavior by altering C3/C3a-C3aR signaling to impact microglia polarization in the CUMS model. Background: Major depressive disorder (MDD) has been…MR Conditional Labeling for DBS – Basic Physics for the Non-Specialist
Objective: A non-technical overview of the physics behind MR Conditional labeling for DBS devices and the implications for diagnostic imaging. Background: MRI is the recommended…An Analysis of Health Care Utilization in Functional Movement Disorders: Does Diagnosis Make a Difference?
Objective: To investigate the impact of diagnosis on health care utilization (HCU) in the functional movement disorders (FMD) population. Background: FMD patients are considered to…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.