MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • MDS Virtual Congress 2020

    Predictors of Underlying Neurodegeneration in Drug-Induced Parkinsonism

    W. Aamodt, J. Dubroff, G. Cheng, B. Taylor, S. Wood, J. Duda, J. Morley (Philadelphia, PA, USA)

    Objective: To examine a cohort of Veterans with drug-induced parkinsonism (DIP) using [123I]Ioflupane single photon emission computed tomography (DAT-SPECT) to identify those with nigrostriatal degeneration…
  • MDS Virtual Congress 2020

    Inter-network connectivity dynamics underlie compensatory mechanisms in prodromal Parkinson’s disease

    A. Droby, N. Omer, M. Artzi, D. Ban-Bashat, M. Hutchison, J. Cederbaum, N. Giladi, A. Mirelman, A. Thaler (Tel Aviv, Israel)

    Objective: We aimed to investigate the dynamics of inter-network connectivity among non-manifesting GBA and LRRK2 mutation carriers. Background: The prodromal phase of Parkinson’s disease (PD)…
  • MDS Virtual Congress 2020

    Hyposmia as a biomarker in patients with Parkinson’s disease and atypical Parkinsonism

    S. Kumaran, A. Ankeeta, S. Chaudhary, P. Bhat, V. Goyal (New Delhi, India)

    Objective: To investigate neural correlates associated with olfactory dysfunction using fMRI and EEG in Parkinsonism. Background: Patients with Parkinsonism experience non-motor symptoms during the onset…
  • MDS Virtual Congress 2020

    Levodopa-induced dyskinesias and substantia nigra dopamine D3 receptor availability in Parkinson’s disease

    G. Pagano, S. Molloy, P. Bain, E. Rabiner, K. Chaudhuri, D. Brooks, N. Pavese (Basel, Switzerland)

    Objective: To investigate with PET and the radioligand [11C]PHNO whether levodopa-induced dyskinesias in Parkinson disease (PD) are associated with dopamine-D3 receptor (D3R) overexpression in substantia nigra…
  • MDS Virtual Congress 2020

    Application of substantia nigra feature extraction in the progression of Parkinson’s disease based on magnitude image of susceptibility weighted imaging

    Q. Ren, B. Zhang, J. Zhang, X. Shuai, X. Nan, Y. Ge, X. Meng, C. Zhao (Qingdao, China)

    Objective: This present study was aimed to investigate the potential value of the substantia nigra (SN) radiomic feature for the prediction of PD progression. Background:…
  • MDS Virtual Congress 2020

    Impairment of the mesocortical dopamine system in Parkinson’s disease patients with freezing of gait in a multimodal imaging approach

    K. Steidel, M. Ruppert, A. Greuel, I. Palaghia, J. Hammes, T. van Eimeren, L. Timmermann, M. Tittgemeyer, A. Drzezga, C. Eggers (Marburg, Germany)

    Objective: To investigate the involvement of dopaminergic systems in Parkinson’s disease (PD) patients with freezing of gait (FOG) using a multimodal assessment involving 18 F-DOPA-PET…
  • MDS Virtual Congress 2020

    Functional connectivity and volumetric data improve prediction of DBS outcomes

    J. Younce, M. Campbell, J. Perlmutter, S. Norris (St Louis, MO, USA)

    Objective: To determine the clinical utility of neuroimaging markers to predict motor outcomes for deep brain stimulation (DBS) of the subthalamic nucleus (STN) in Parkinson…
  • MDS Virtual Congress 2020

    Rhythmic activity of subthalamic neurons during externally and internally generated movements in Parkinson’s disease

    V. Filyushkina, E. Belova, S. Usova, V. Popov, A. Tomskiy, A. Sedov (Moscow, Russian Federation)

    Objective: To find the specificity of neuronal responses in the subthalamic nucleus during externally and internally generated voluntary movements in Parkinson’s disease. Background: The motor…
  • MDS Virtual Congress 2020

    Genetic Profiling of Early Synucleinopathy in Rat Nigrostriatal Dopamine Neurons

    J. Patterson, C. Kemp, M. Duffy, J. Howe, C. Russell, A. Stoll, K. Miller, J. Beck, S. Counts, K. Steece-Collier, K. Luk, C. Sortwell (Grand Rapids, MI, USA)

    Objective: Identification of changes in gene expression in rat nigral neurons associated with early phases of synucleinopathy. Background: Early phases of synucleinopathies such as Parkinson’s…
  • MDS Virtual Congress 2020

    Progression in Parkinson’s disease: Variation in motor and non-motor symptoms severity and predictors of decline in cognition, motor function, incapacity and Health Related Quality of Life

    P. Bugalho, F. Ladeira, R. Barbosa, J. Marto, C. Borbinha, M. Salavisa, M. Saraiva, L. Conceição, M. Fernandes, B. Meira (Lisboa, Portugal)

    Objective: Assess the progression of motor and non-motor symptoms in Parkinson's Disease (PD) and predictors of cognitive, motor, activities of daily living (ADL) and Health…
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