Mov Disord Vol 35, Suppl 1 Archives - Page 124 of 149 - MDS Abstracts

MDS Virtual Congress 2020
Identifying Neuropsychiatric Profiles in Parkinson’s disease, Dementia with Lewy Bodies and Alzheimer’s disease
D. Smith, P. Donaghy, B. Galna, A. Yarnall, J.P Taylor, D. Burn, A. Thomas, L. Rochester, R. Mc Ardle, R. Lawson (Newcastle upon Tyne, United Kingdom)
Objective: To compare Neuropsychiatric symptoms (NPS) in participants with Parkinson’s disease (PD), Parkinson’s disease with dementia (PDD), dementia with Lewy bodies (DLB), Alzheimer’s disease (AD)…
MDS Virtual Congress 2020
Anxiety disorders are associated with verbal memory impairment in Parkinson’s disease
N. Dissanayaka, E. Forbes, J. Yang, J. O'Sullivan, D. Copland, K. McMahon, L. Mitchell, G. Byrne (Brisbane, Australia)
Objective: The present study aimed to investigate the association between anxiety disorders and memory impairment in Parkinson’s disease.The present study aimed to investigate the association…
MDS Virtual Congress 2020
Behavioral and Psychological Symptoms in Patients with Movement Disorders
M. Kulsum, S. Anand, H. Kumar (Kolkata,, India)
Objective: To find out the prevalence of neuropsychiatric symptoms in patients with Movement Disorders. To find out the relationship between cognitive impairment and neuropsychiatric symptoms…
MDS Virtual Congress 2020
Parkinson’s Disease Clinical Subtypes: Symptom Progression, Dementia, and Mortality
P. Myers, J. Jackson, A. Clover, C. Lessov-Schlaggar, E. Foster, J. Perlmutter, M. Campbell (St. Louis, MO, USA)
Objective: Identify Parkinson's disease (PD) clinical subtypes using multi-domain classification; determine subtype symptom progression; assess subtype clinical utility. Background: People with PD present with combinations…
MDS Virtual Congress 2020
Hand Fine Motor Performance Capacity is Associated with the Cognition in People with Moderate to Advanced Parkinson’s disease
S. Tan, C.T Hong, T.H Liou (New Taipei City, Taiwan)
Objective: This study aims to investigate the association between the hand fine motor performance with the cognitive dysfunction in people with moderate and severe PD.…
MDS Virtual Congress 2020
Parkinson’s disease polygenic risk score and brain structure in neurologically healthy individuals
N. Abbasi, L. Krohn, U. Vainik, Z. Gan-Or, A. Dagher (Montreal, QC, Canada)
Objective: To investigate the relationship between Parkinson’s disease-polygenic risk score (PD-PRS) and brain morphology in a large sample of healthy individuals. Background: PD is caused…
MDS Virtual Congress 2020
Beta-Glucocerebrosidase Activity in GBA-linked Parkinson’s Disease: The Type of Mutation Matters
Y.E Huh, M.S Chiang, J. Locascio, Z. Liao, G. Liu, K. Choudhury, Y. Kuras, I. Tuncali, A. Videnovic, A. Hunt, M. Schwarzschild, A. Hung, T. Herrington, M. Hayes, B. Hyman, A.M Wills, S. Gomperts, J. Growdon, S. Sardi, C. Scherzer (Boston, MA, USA)
Objective: To test the relationship between clinically relevant types of GBA mutations (none, risk variants, mild mutations, severe mutations) and beta-glucocerebrosidase activity in patients with…
MDS Virtual Congress 2020
Parkinson’s disease polygenic risk prediction and haplotype analysis in a South American cohort
D. Loesch, A. Horimoto, E. Sarihan, M. Cornejo-Olivas, L. Torres, M. Inca-Martinez, P. Mazzetti, C. Cosentino, E. Dieguez, V. Raggio, A. Lescano, V. Tumas, V. Borges, H. Ferraz, C. Rieder, A. Schumacher-Schuh, B. Lopes Santos-Lobato, C. Velez-Pardo, M. Jimenez-Del-Rio, F. Lopera, P. Chana-Cuevas, W. Fernandez, G. Arboleda, H. Arboleda, C. Arboleda-Bustos, D. Yearout, C. Zabetian, T. Thornton, T. O'Connor, I. Mata (Baltimore, MD, USA)
Objective: We aim to evaluate the performance of a Parkinson’s disease (PD) polygenic risk score (PRS), estimated using genome-wide association (GWAS) data from a European…
MDS Virtual Congress 2020
GPNMB protein levels in CNS are modulated by PD risk variant rs199347
Y. Seo, M. Diaz Ortiz, D. Weintraub, V. Van Deerlin, J. Trojanowski, A. Chen-Plotkin (Philadelphia, PA, USA)
Objective: This study evaluates protein quantitative trait loci (pQTL) effect of single nucleotide polymorphism (SNP) rs199347 in modulating glycoprotein non-metastatic melanoma protein B (GPNMB) expression…
MDS Virtual Congress 2020
SNPs in SNCA, MCCC1, DLG2, GBF1, and MBNL2 are associated with Parkinson’s disease in southern Chinese populations
A. Zhao, Y. Li, M. Niu, G. Li, N. Luo, L. Zhou, W. Kang, J. Liu (Shanghai, China)
Objective: This study aimed to replicate the relationship between 12 novel SNPs of 12 genes and PD risk in southern Chinese populations. Background: Numerous single-nucleotide polymorphisms (SNPs), which have…