MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • MDS Virtual Congress 2020

    Association between BDNF Val66Met polymorphism and mild behavioral impairment in patients with Parkinson’s patients

    M. Ramezani, J. Ruskey, K. Martens, E. Leveille, Z. Javer, I. Kathol, M. Kibreab, T. Hammer, J. Cheetham, J. Sarna, D. Martino, G. Pfeffer, Z. Gan-Or, Z. Ismail, O. Monchi (Calgary, AB, Canada)

    Objective: This study investigates if PD patients with Brain-derived-neurotrophic-factor (BNDF) Met allele are more likely to have Mild behavioral impairment (MBI). And whether Met allele…
  • MDS Virtual Congress 2020

    The Personalized Parkinson Project – data quality enhancing strategies

    B. Bloem, L. Evers, T. vande Zande, R. Kapur, M. Meinders, W. Marks, Jr (Nijmegen, Netherlands)

    Objective: Demonstrate the impact of quality enhancing strategies in the Personalized Parkinson Project. Background: Increasingly, the scientific community uses data from longitudinal observational patient cohorts…
  • MDS Virtual Congress 2020

    AADC gene therapy administered via a posterior approach: 18-month results from the PD-1102 trial in advanced Parkinson’s disease

    S. Factor, A. Van Laar, R. Richardson, C. Christine, P. Larson, S. Kostyk, R. Lonser, C. Li, G. Liang, A. Meier, E. Fine, R. Gross (Atlanta, GA, USA)

    Objective: To report 18-month safety and clinical outcomes from a phase 1, open-label trial of VY-AADC01 (NBIb-1817) for Parkinson’s disease (PD) patients with motor fluctuations.…
  • MDS Virtual Congress 2020

    Comparison of Categorical- and Verbatim-Reported Postural Instability Symptoms Among Fox Insight Parkinson Research Participants

    M. Javidnia, L. Arbatti, A. Hosamath, S. Eberly, D. Oakes, A. Nguyen, I. Shoulson (Rochester, NY, USA)

    Objective: To analyze verbatim patient-reported problems compared with ordinal measures referable to Postural Instability (PI) symptoms in the Fox Insight (FI) observational study. Background: FI…
  • MDS Virtual Congress 2020

    Prospective assessment of the lessebo effect in placebo-controlled randomized trials using an expectancy questionnaire

    T. Mestre, E. Macklin, C. Coffey, M. Kostrzebski, A. Ascherio, J. Ferreira, M. Schwarzschild, T. Simuni, A. Lang (Ottawa, ON, Canada)

    Objective: To prospectively measure the lessebo effect using an expectancy questionnaire (EQ). Background: The presence of a placebo arm in a randomized controlled trial has…
  • MDS Virtual Congress 2020

    Therapeutic Benefits of Music for Three Types of Neurological Disorders: an fNIRS Study Protocol for Controlled Trial in Dalian, China, Part 1-Parkinson’s Disease

    LL. Pu, Z.H Liang, W.C Tang, F.Y Cong, B.W Zhang, N.K Qureshi, J. Ly, T. Li (Dalian, China)

    Objective: It is investigated that the external auditory stimuli affect motor synchronization and control in patients with PD,and further studied that how music therapy or other…
  • MDS Virtual Congress 2020

    Improving automaticity of walking in Parkinson’s disease: Levodopa or Donepezil?

    S. Stuart, R. Morris, A. Giritharan, J. Quinn, J. Nutt, M. Mancini (Newcastle upon Tyne, United Kingdom)

    Objective: Determine whether levodopa replacement or cholinergic augmentation improve automaticity of walking in people with Parkinson’s disease (PD). Background: Degradation of dopaminergic striatal mechanisms of…
  • MDS Virtual Congress 2020

    Using a Delphi process to inform the design of disease modifying trials in Parkinson’s disease

    M. Zeissler, R. Windle, K. McFarthing, K. Raphael, G. Rafaloff, C. Carroll (Plymouth, United Kingdom)

    Objective: To consolidate current opinion on trial methodology of disease modifying therapies (DMTs) for Parkinson’s disease (PD) and establish consensus on a core protocol for…
  • MDS Virtual Congress 2020

    Levodopa and dopamine agonists dosage changes after Opicapone introduction

    N. Caballol, A. Planas-Ballvé, A. Ávila (Sant Joan Despí, Spain)

    Objective: We aim to analyze changes in levodopa and dopamine agonists (DA) dosage after introduction of opicapone (OPC) in a daily clinical practice setting. Background:…
  • MDS Virtual Congress 2020

    Maintenance of safinamide 100 mg daily long-term

    N. FONCEA (Galdakao, Spain)

    Objective: Evaluating the maintenance of safinamide 100 mg daily as a long-term treatment Background: The effects of safinamide were investigated in studies 016, 018 and…
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