Improving automaticity of walking in Parkinson’s disease: Levodopa or Donepezil?
Objective: Determine whether levodopa replacement or cholinergic augmentation improve automaticity of walking in people with Parkinson’s disease (PD). Background: Degradation of dopaminergic striatal mechanisms of…Using a Delphi process to inform the design of disease modifying trials in Parkinson’s disease
Objective: To consolidate current opinion on trial methodology of disease modifying therapies (DMTs) for Parkinson’s disease (PD) and establish consensus on a core protocol for…Levodopa and dopamine agonists dosage changes after Opicapone introduction
Objective: We aim to analyze changes in levodopa and dopamine agonists (DA) dosage after introduction of opicapone (OPC) in a daily clinical practice setting. Background:…Maintenance of safinamide 100 mg daily long-term
Objective: Evaluating the maintenance of safinamide 100 mg daily as a long-term treatment Background: The effects of safinamide were investigated in studies 016, 018 and…Frequency and risk factors of dopamine agonist-induced peripheral edema in patients with Parkinson’s disease
Objective: To determine the frequency and risk factors of peripheral edema (PE) development and whether discontinuation of the drug is enough for treatment. To determine…Vitamin D assessment in patents with Parkinson’s disease
Objective: Analysis of the effectiveness of vitamin D in patients with PD depending on clinical manifestations and concentration levels of 25 (OH) D. Background: Recent…Management of parkinsonian patients with long-term DBS and incomplete control of symptoms
Objective: We want to evaluate if apomorphine infusions can improve symptom control in PD patients with long standing DBS and functional decline. Background: Deep brain stimulation…Efficacy and safety of istradefylline in Parkinson’s disease patients with postural abnormality: Results from a multicenter, open-label study in Japan
Objective: To investigate the efficacy and safety of istradefylline for the treatment of postural abnormality in patients with Parkinson’s disease (PD). Background: Postural abnormality in…Body Weight-Supported Treadmill Training Improves Walking Function in Multiple System Atrophy: A Case Report
Objective: Multiple system atrophy (MSA) is a rapidly progressive synucleinopathy involving autonomic dysfunction and impaired mobility. MSA has been further sub-classified into two phenotypes: parkinsonian…Characterising Oromandibular Dystonia in Multiple System Atrophy: A video analysis
Objective: To characterise craniofacial manifestations in patients with MSA and explore the relationship between OMD and other related symptoms and treatment. Background: According to the…
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