Orthostatic hypotension in early onset Parkinson’s disease
Objective: To investigate Orthostatic hypotension (OH) feature in early onset Parkinson's disease (EOPD) , especially delayed OH and acute OH post drug. To explore OH…The effect of exercise on pain in Parkinson’s disease: A protocol for a systematic review
Objective: To perform and present a systematic review assessing the effects of exercise on pain in people with Parkinson’s disease (PD) (prospero registration CRD42019129154). Background:…Association between essential tremor, constipation, and the risk of developing Parkinson’s disease
Objective: To evaluate the association between constipation and the risk of Parkinson’s disease (PD) in patients with a prior history of essential tremor (ET). Background:…Odor Identification as a Biomarker of Incident Cognitive Impairment and its Correlation with Neuropathology in the Rush MAP
Objective: Evaluate the neuropathological correlates and prospective incident cognitive and motor changes associated with odor identification (OI) in cognitively normal (CN) subjects. Background: Hyposmia is…Disease progression characterized by motor performance, dopaminergic neurodegeneration and T cell infiltration in the transgenic hm2-α-SYN-39 mouse model of Parkinson´s disease
Objective: To study disease progression in the transgenic (tg) hm2-α-SYN-39 mouse model of Parkinson´s disease (PD) by assessment of motor performance, dopaminergic neurodegeneration and T…Identifying biomarkers to predict disease progression in early stage Parkinson’s disease patients
Objective: To evaluate the sensitivity of instrumented measures of motor dysfunction and candidate serological markers of disease to predict disease progression in de novo Parkinson’s…Minor hallucinations in Parkinson’s disease are associated with increased neurofilament plasma levels and reduced white-matter integrity in the inferior longitudinal fasciculus
Objective: To examine whether patients with Parkinson's disease (PD) and isolated minor hallucinations have increased plasma neurofilament light chain (NfL) levels and/or differences in white…Depression in patients with Parkinson’s disease
Objective: The objective of this study was to correlate PD severity with depression. Background: Depression is the most common psychiatric disorder in patients with PD. In…Severity of Motor Symptoms in Parkinson’s Disease in Kazakhstan (on the example of the city of Almaty)
Objective: Determine the severity of motor symptoms with Parkinson's disease using the MDS-UPDRS scale. Background: Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by…Safety and efficacy of istradefylline, an adenosine A2A receptor antagonist, as a function of baseline dyskinesia (BL-dyskinesia) in Parkinson’s disease (PD): A pooled analysis of 4 studies
Objective: To evaluate the effect of BL-dyskinesia on the efficacy and safety of istradefylline in 4 randomized, placebo-controlled, double-blind, phase 2b/3 trials. Background: Istradefylline, a…
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