Clinical factors associated with neuronal loss in the substantia nigra
Objective: To explore (additional) clinical features associated with nigral neuronal loss that could potentially be included in the criteria for prodromal Parkinson’s disease (PD). Background:…Deep brain stimulation and cognitive decline in Parkinson’s disease: The predictive value of Alternate Fluency test
Objective: To study the impact of subthalamic nucleus deep brain stimulation (STN-DBS) on executive function using Alternate Fluency Test (AFT) and to investigate predictors for…Comparative analysis of cognitive function between unilaterally and bilaterally affected Parkinson’s disease
Objective: To compare the cognitive function between unilateral and bilateral PD to identify whether worse cognitive impairment underlies in the bilateral group who had greater…Increased neurofilament light chain plasma levels as a biological marker of mild cognitive impairment in Parkinson’s disease
Objective: To examine whether PD-MCI patients have increased plasma neurofilament light chain (NfL) levels compared to PD with normal cognition (PD-NC) and healthy controls (HC).…Clock Drawing Test does not Differentiate Alzheimer’s Disease from Parkinson’s Disease Dementia
Objective: Our focus was on comparing the performance of CDT and MMSE in Parkinson’s Disease Dementia (PDD) and Alzheimer’s Disease (AD) patients. Background: The mini…Impulsive Control Behaviours in Patients with GBA, PARK2 and without Mutations in Genes Associated to Parkinson’s Disease
Objective: Aim of the study was to assess prevalence and severity of ICBs in PD patients with GBA mutations. Background: Parkinson disease (PD) is a…Contribution of coding/noncoding variants in NUS1 to late-onset sporadic Parkinson’s disease
Objective: Here, we designed a case-control study to analyze WGS variants in NUS1 coding regions and NUS1 related non-coding regions to investigate the relative contribution…Early predictors of Parkinson’s disease and prognosis in relatives
Objective: To study early clinical and biochemical markers of Parkinson's disease (PD) in relatives of Uzbek nationality. Background: Parkinson's disease is a neurodegenerative hereditary disease…DJ1 and α-Synuclein as CSF biomarkers and gene polymorphisms: association with clinical parameters in Parkinson’s disease
Objective: To analyze the CSF α-Synuclein and DJ1 Biomarkers correlating with SNCA and DJ1 gene polymorphisms and clinical parameters in PD. Background: Currently there is…Multiplex biomarker discovery for diagnostic and progression markers for Parkinson’s disease with the proximity extension assay technology on inflammation-related analytes
Objective: To identify diagnostic and progression biomarkers in the longitudinal DeNoPa cohort of (at enrolment) de novo Parkinson’s disease (PD) and healthy controls (HC) using…
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