The role of dopamine mis-metabolism in preclinical Parkinson’s disease olfactory deficits
Objective: To gain an understanding of the underlying pathological mechanisms of Parkinson’s disease (PD)-related hyposmia using post-mortem human olfactory bulbs and an in vivo model…Serum molecular markers and non-motor symptoms in Parkinson’s disease
Objective: The aim of this study was to examine the association between several serum molecular markers and different measures of non-motor symptom burden in PD.…Poor Sleep Quality is Associated With Fatigue in Early Parkinson’s Disease: A Longitudinal Study in the Early Parkinson’s Disease Longitudinal Singapore Study (PALS) Cohort
Objective: This study aims to explore the associations between baseline sleep quality and the progression of other non-motor symptoms in early Parkinson’s disease (PD). Background:…Trajectories of pain in newly diagnosed Parkinson’s disease
Objective: To determine the frequency and stability of pain over time in a cohort of patients with early Parkinson’s disease (PD). Background: Pain is a…Frequency of Wearing-Off Symptoms in Parkinson’s disease Fluctuators: An on/off evaluation
Objective: To determine if the frequency of wearing-off symptoms in Parkinson’s disease (PD) patients who report fluctuations differs from patients without fluctuations. Background: Wearing-off, the…Difference in olfactory impairment between tremor dominant and akinetic rigid dominant Parkinson’s disease patients
Objective: To investigate difference in olfactory impairment between tremor dominant (TD) and akinetic rigid dominant (ARD) Parkinson’s disease patients. Background: PD can be classified in…Non-motor symptoms in Parkinson’s disease and the model of Braak
Objective: We aimed to determine different subtypes of Parkinson’s disease (PD) patients using clinical data from the appearance chronology of their non-motor and motor symptoms…An objective comparison of forward and backward postural instability in early Parkinson’s disease
Objective: To test if perturbations that induce backward or forward steps are better for distinguishing reactive stepping impairment between people with mild-to-moderate early PD and…Mixed pathologies in pancreatic beta-cells from subjects with neurodegenerative diseases and their interaction with prion protein
Objective: We studied whether, as in the brain, pancreatic -cells of subjects with neurodegenerative diseases also present co-occurrence of other misfolded proteins. Furthermore, we also assessed…Naturalistic study of depression and Parkinson´s Disease in a third level of attention in Mexico City
Objective: Describe the sociodemographic and clinical variables of patients with Parkinson's disease (PD) diagnosed with major depressive disorder (MDD) in the outpatient clinic (OC) of…
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