Visualization of Nigrosome 1 at 3T MRI and 18F-DOPA PET for the diagnosis of Parkinson´s disease
Objective: To determine and compare the utility of Nigrosome 1 at 3T MRI and 18F-DOPA PET for the diagnosis of Parkinson´s disease. Background: Differential diagnosis…Frailty as clinical modulator of brain damage and progression in Parkinson’s disease
Objective: To evaluate the prevalence of frailty and correlation with motor and non-motor symptoms as well as MRI atrophy and white matter hyperintensities in Parkinson's…Distinct compensatory and maladaptive wiring patterns in genotypic Parkinson’s disease
Objective: Although disease networks have been identified in Parkinson’s disease (PD) using functional imaging, it is unclear whether these represent maladaptive or compensatory responses to…Regional free-water differentially associated with glial activation, neuroinflammation, and neurodegeneration in de novo Parkinson’s disease
Objective: Assess to what extent free-water(FW) as measured by diffusion-weighted MRI(dMRI) is a neuroimaging marker of glial activation, neuroinflammation, and neurodegeneration in de novo Parkinson’s disease(PD) patients from…Deficient Balance Mechanisms during Walking in People with Parkinson’s Disease
Objective: Investigate whether people with Parkinson’s disease (PD) have deficient balance mechanisms following visual perturbations during walking. Background: We recently showed that maintaining upright balance…Rhythmic movements decompose in Parkinson’s disease with worse disease severity at low frequencies: akinesia or impaired ability to move more slowly than comfortable?
Objective: To explore the relationship between disease severity, minimum comfortable velocity and dwell time in Parkinson's disease. Background: People find it hard to move smoothly…The dysfunctional autonomic function and “dysfunctional” fatigue in drug naïve Parkinson’s disease
Objective: In the present study, the relationship between fatigue and autonomic dysfunction in drug-naïve PD patients was investigated. Background: Fatigue is a common and disabling…Clinical characteristics of pain in Parkinson’s disease dementia
Objective: The aim of this study was the assess the prevalence of pain in Parkinson’s disease dementia, its clinical characteristics, and correlations with motor part…Long-term quality of life after subthalamic deep brain stimulation depends on non-motor symptoms in Parkinson’s disease
Objective: To predict 36-month follow-up quality of life (QoL) outcome after bilateral subthalamic nucleus deep brain stimulation (STN-DBS) in Parkinson’s disease (PD). Background: STN-DBS improves…Depression in Parkinson’s Disease: perspectives from an Australian cohort
Objective: This study aimed to identify clinical predictors and management implications for depression in an Australian cohort of Parkinson’s disease (PD) patients. Background: Depression is…
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