Association between quality of life and physical functions in patients with idiopathic Parkinson’s disease
Objective: The aim was to investigate the association between health-related quality of life and physical functions in the patients with idiopathic Parkinson's disease (PD). Background:…Computing algorithms can detect bradykinesia from smartphone videos
Objective: To investigate whether computer vision algorithms can detect bradykinesia using standard smartphone video alone. Background: Bradykinesia is the core clinical feature of Parkinson’s disease…Time-Frequency analysis of Gait-EEG signals for freezing of gait in a PD patient
Objective: We used Gait-EEG to simultaneously record the three-axis acceleration and EEG during a PD patient’s timed-up-and-go (TUG) task, aimed to accurate identify and detect the…Modeling the Effect of Patient’s Perception of Non-Motor and Motor Function on Parkinson’s Disease Severity
Objective: To develop optimal models of patients' perception of non-motor and motor function on objectively measured Parkinson's disease (PD) severity. Background: There is increased interest…An Internet of Things system for patient empowerment: a case study on measuring patients’ understanding of causal relationships between symptoms and behaviour
Objective: To evaluate the ability of patients to understand causal relationships between disease symptoms and behaviour presented from synthetic representative cases using the system. Secondary…Prefrontal cortex high beta power correlates with the severity of anxiety and depression in Parkinson’s disease patients
Objective: To investigate the neural correlates of anxiety and depression in PD patients and to develop a novel neurostimulation therapy for these non-motor symptoms. Background:…The effects of onabotulinum toxin on neurophysiological tests in patients with hemifacial spasm
Objective: We aimed to investigate effects of onabotulinum toxin (OnaBoNT) on clinical and neurophysiological findings of patients with hemifacial spasm (HFS). Background: There is a…No evidence for early emotional processing in the subthalamic nucleus – a single neuron study
Objective: To provide evidence of early emotional processing at the single-neuron level in the STN. Background: A fast response to coarse threat signals in the…Expression analysis of candidate genes in a cell model of affected and unaffected THAP1 mutation carriers and controls
Objective: To evaluate the role of expressional changes in carriers of a THAP1 mutation in relation to penetrance of dystonia. Background: THAP1 encodes a transcription…Social Cognition and Habituation in Cervical Dystonia
Objective: To assess social cognition in people with cervical dystonia (CD). Background: Anxiety and depression are common and disabling comorbidities in CD. Difficulties in processing…
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