Does information from the Personal KinetiGraph™ (PKG) influence neurologists´ treatment decisions?
Objective: To evaluate if PKG data influences neurologists´ treatment decisions in routine clinical care of patients with Parkinson´s disease. Background: The PKG movement recording system is…Application of the Movement Disorders Society Criteria for diagnosis of Progressive Supranuclear Palsy
Objective: Analyze the sensitivity, specificity of the Movement Disorders Society (MDS) criteria for progressive supranuclear palsy (PSP) and apply the multiple allocation extinction (MAX) rules…Limitations of Curcumin as a Therapeutic Agent in Rotenone Induced Dopaminergic Neurodegeneration: Insights from Drosophila Model of Parkinson’s Disease
Objective: To understand the efficacy of curcumin in rotenone induced Drosophila model of Parkinson’s disease. Background: Parkinson’s disease (PD) is the second most common neurodegenerative…Medical management after subthalamic nucleus deep brain stimulation in patients with Parkinson’s Disease
Objective: The present study aims to: i) systematically evaluate literature data on acute medical management after subthalamic nucleus (STN) deep brain stimulation (DBS) and, ii)…Safety and Tolerability of opicapone in Parkinson’s disease
Objective: To evaluate safety and tolerability of opicapone as an add‐on treatment to levodopa in Parkinson's disease (PD) patients. Background: Opicapone is a recently approved…Gender differences of fatigue characteristics in people with Parkinson’s disease
Objective: To investigate gender differences in fatigue characteristics in people with Parkinson’s disease. Background: Fatigue is a common problem among people with Parkinson’s disease. It…Language disorders in Progressive Supranuclear Palsy: an underestimated condition?
Objective: We aimed to investigate executive functions and languages abilities in PSP patients and in Progressive Supranuclear Palsy (PSP) subgroups [PSP-Richardson’s Syndrome (PSP-RS) and PSP-non-RS]…Levodopa response in later stages of Parkinson’s disease: a case-control study
Objective: To compare the response of motor and non-motor symptoms (NMS) to a L-dopa challenge test between late stage (LS) PD patients and advanced stage…Swallowing assessment in Parkinson’s Disease using Dynamic Magnetic Resonance Imaging (dMRI)
Objective: To evaluate any dysphagia-signs in Parkinson’s disease (PD) with technique that is non-invasive, without-radiation-exposure and gives good soft-tissue contrast. Background: Swallowing, a basic oromotor…Impaired lysosomal catabolism of alpha-synuclein in parkinsonian LRRK2(R1441G) mutant mouse embryonic fibroblasts
Objective: Using a unique fluorescence-based flow cytometry assay on LRRK2(R1441G) mutant mouse embryonic fibroblasts (MEFs) to elucidate whether pathogenic LRRK2 mutation affects cellular lysosomal degradation…
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