MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2019 International Congress

    Measurement properties of the MDS-NMS Non-motor Fluctuations Subscale

    MJ. Forjaz, A. Ayala, C. Rodriguez-Blazquez, A. Schrag, D. Weintraub, A. Rizos, KR. Chaudhuri, P. Martinez-Martin (Philadelphia, PA, USA)

    Objective: This study aims at describing the measurement properties of the Non-motor Fluctuations (NMFs) subscale of the Movement Disorders Society Non-Motor Rating Scale (MDS-NMS) according…
  • 2019 International Congress

    Levocarb-induced diplopia in idiopathic Parkinson’s disease: a case report

    S. Joza, F. Ba (Edmonton, AB, Canada)

    Objective: To present a case report of Levocarb-induced diplopia in idiopathic Parkinson’s disease. Background: Parkinson’s disease (PD) is a common neurodegenerative disorder characterized by a…
  • 2019 International Congress

    Non-motor symptoms in Parkinson disease motor subtypes: a study using the new MDS-NMS

    P. Martinez-Martin, C. Rodriguez-Blazquez, A. Schrag, D. Weintraub, A. Rizos, KR. Chaudhuri (Madrid, Spain)

    Objective: To analyze the prevalence and severity of non-motor symptoms (NMS) in Parkinson disease (PD) motor subtypes (tremor-dominant, TD; postural instability/gait disorder, PIGD; and indeterminate),…
  • 2019 International Congress

    Motor Networks in Tremor-Dominant Parkinson’s Disease. A resting-state functional MRI and diffusion tensor imaging analysis.

    Z. Chappell, H. Wilson, M. Politis (London, United Kingdom)

    Objective: To investigate the integrity of cerebellothalamocortical circuit (CTCC) and basal ganglia-cortical loop (BGCL) connectivity in tremor-dominant PD (TD-PD) and compare with a group of akinetic-rigid…
  • 2019 International Congress

    Composite UHDRS shows extensive spatial correlation with grey matter and white matter volume in Huntington’s disease gene carriers

    C. Estevez-Fraga, E. Johnson, F. Rodrigues, P. Zeun, A. Durr, D. Langbehn, B. Leavitt, R. Roos, S. Gregory, R. Scahill, G. Rees, S. Tabrizi (London, United Kingdom)

    Objective: This work sought to determine the structural correlates of variability in cUHDRS in HD gene expansion carriers (HDGC). Background: Symbol digit modalities test (SDMT),…
  • 2019 International Congress

    Association of MRI-derived estimated brain age and cognitive ability in Parkinson’s disease

    K-L. Horne, R. Shoorangiz, L. Livingston, S. Grenfell, M. Almuqbel, B. Young, M. Pascoe, M. Livingstone, M. Macaskill, D. Myall, T. Pitcher, T. Anderson, J. Dalrymple-Alford, T. Melzer (Chrsitchurch, New Zealand)

    Objective: To characterise MRI-derived structural age-related brain health in Parkinson’s disease (PD) patients as a function of cognitive ability. Background: Normal ageing produces a stereotypical…
  • 2019 International Congress

    Relationship between striatal dopamine depletion and various non-motor symptoms in non-demented patients with Parkinson’s disease: a pilot study

    JY. Lee, H. Ju, K. Im, MY. Ahn, KY. Kwon (Seoul, Republic of Korea)

    Objective: We aimed to investigate associations of striatal dopamine uptake and various non-motor symptoms in non-demented patients with Parkinson’s disease (PD). Background: Dopamine transporter (DAT)…
  • 2019 International Congress

    Investigation of 531 cases of neuromelanin sensitive imaging, about its characteristics by disease

    K. Matsuura, Y. Ii, M. Maeda, K. Tabei, M. Umino, H. Tomimoto (Tsu, Japan)

    Objective: To investigate the utility of Neuro-Melanin sensitive MRI (NMI) by 3T MRI for diagnosis, the relationship and severity in Parkinson's disease (PD) and related…
  • 2019 International Congress

    Mitochondrial Complex 1, Sigma 1 Receptor and Synaptic Vesicle protein 2A density in early de novo patients with Parkinson’s Disease: pilot PET data

    G. Pagano, H. Wilson, A. Mansur, S. Caminiti, R. Comley, H. Tsukada, R. Gunn, E. Rabiner, M. Politis (London, United Kingdom)

    Objective: In this study, we evaluated the density of Mitochondrial complex 1 (MC1), sigma 1 receptor (s1R) and Synaptic Vesicle protein 2A (SV2A) in early…
  • 2019 International Congress

    Potential involvement of the caudate nucleus in GBA-associated Parkinson’s disease

    MC. Ruppert, A. Greuel, M. Tahmasian, F. Maier, T. van Eimeren, K. Lohmann, L. Timmermann, M. Tittgemeyer, A. Drzezga, C. Eggers (Marburg, Germany)

    Objective: Multimodal functional assessment of striatocortical loop integrity in Parkinson’s Disease (PD) patients with and without GBA variants Background: Biallelic GBA mutations provoke the lysosomal…
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