Low doses of scopolamine exacerbates dementia among Drosophila with Parkinson’s disease pathophysiology
Objective: To assess the non-inducing doses of scopolamine (SCL) on the memory function of Drosophila previously induced with Parkinson's disease phenotype. Background: A large body…Complement C3a receptor antagonist attenuates tau hyperphosphorylation via glycogen synthase kinase 3β signaling pathways
Objective: To investigate the role and mechanism of C3a receptor in okadaic acid（OA） induced SH-SY5Y cells tau hyperphosphorylation model Background: Neurofibrillary tangles aggregated from hyperphosphorylated…Tau pathology is associated to cognitive and not motor function in Parkinson’s disease
Objective: To define the association of different cerebrospinal fluid (CSF) biomarkers reflecting Aß and Tau pathology or synaptic function with motor and/or cognitive function in…Cognitive profile of degenerative parkinsonian syndromes in the French West Indies and relationship with eye movements recordings
Objective: To analyze the cognitive profile of patients with degenerative parkinsonian syndromes in the French West Indies and explore the correlations between cognitive deficits and…Neurocognitive changes after STN-DBS among PD patients – a 2-year follow-up study in Hong Kong
Objective: The study aimed to examine the neurocognitive changes following STN-DBS in patients with PD. Background: Neurocognitive evaluation is a standard procedure preoperatively in patients…Movement and symptom-modulated local field potentials in globus pallidus internus of Parkinson’s disease
Objective: To examine the relationship between local field potential (LFP) activity recorded from directional deep brain stimulation (DBS) leads in the internal segment of the…The Circulatory Levels of Serotonin, Beta endorphin and Dopamine and their relations to Pain Perception in People with Parkinson’s Disease
Objective: 1) to examine circulatory serotonin, beta-endorphin and the dopamine metabolite homovanillic acid (HVA) in people with PD, 2) to explore the relationship of the…Co-administration of levodopa and zonisamide reduces the serotonin transporter expression in a rat model of Parkinson’s disease
Objective: To investigate the change of striatal serotonergic system according to the administration of levodopa and zonisamide (ZNS) on the striatal serotonergic system, we analyzed the…Life expectancy with and without Parkinson’s disease in the general population
Objective: To determine (1) the burden of Parkinson’s disease (PD) in the general population and (2) the life expectancy after the diagnosis of PD. Background:…Antibiotic exposure and Risk for Parkinson’s Disease
Objective: To determine whether antibiotic exposure is associated with Parkinson's disease (PD). Background: Environmental exposures affect the risk of PD and it has been proposed…
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