Structural connectivity changes in prodromal Parkinson’s disease patients: a multimodal MRI study
Objective: We hypothesised that changes in the brain structure and connectivity would be present at this stage. Background: There is wide consensus that prolonged prodromal…Vocal cords electromyography abnormalities in multiple system atrophy phenotypes: relevance for the pathophysiology of stridor
Objective: To define correlations between vocal cords electromyography (EMG) abnormalities and stridor in multiple system atrophy (MSA) phenotypes. Background: MSA is a rare α-synucleinopathy characterized…Estimating the long-term effect of early levodopa treatment initiation in Parkinson’s disease
Objective: Using observational longitudinal data to estimate the long-term effect of the duration of levodopa treatment in the first two years after diagnosis. Background: Levodopa…Automated Quantitative MRI Biomarkers in Differentiation of Progressive Supranuclear Palsy and Multiple System Atrophy from Parkinson Disease
Objective: To explore the relative merits of automated MRI-based volumetric measures over visual assessment in the differential diagnosis of Parkinson's disease (PD), parkinsonian variant of…Relationship of cognitive processing speed with postural stability in non-demented Parkinson’s disease patients
Objective: To measure in PD patients with normal cognitive screening the clinical and instrumental measures of postural stability (PS) and analyze their relationship with cognitive…Characteristic Parkinsonism Questionnaire for the Discrimination of Parkinson’s Disease Dementia from Vascular Dementia
Objective: We have designed a characteristic 8-item parkinsonism questionnaire for the screening of motor dysfunction due to Lewy body dementia (LBD). We aim to test…A novel intermittent control paradigm to investigate oscillatory neuronal activity in the STN
Objective: To present a new methodology of recording STN local field potential (LFP) activity. Background: Recordings of LFPs from the subthalamic nucleus (STN) of patients…The differential role of subthalamic and nigral neurons in gait control in Parkinson´s disease patients
Objective: The aim of the study was to identify and characterize subthalamic (STN) and nigral (SNr) neurons showing gait-related activity changes. 12 Parkinson’s disease (PD)…Ginsenoside Rb1 Prevents MPTP-Induced Changes in Hippocampal Memory via Regulation of the α-Synuclein/PSD-95 Pathway
Objective: To explore the effects of ginsenoside Rb1 on the cognitive impairment of Parkinson’s disease (PD) model. Background: Memory deficiency is a common non-motor symptom…Clinical Profile and Response to EMG-Guided Botulinum toxin (BTX) Injection in Writers’ Cramp (WC)- A Study of 25 Indian Patients
Objective: To study WC and its response to EMG-Guided BTX Background: Despite decades of use and popularity of BTX in WC, there is a paucity of…
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