Differentiating the substantia nigra pars compacta and ventral tegmental area in early-stage Parkinson’s disease using quantitative susceptibility mapping
Objective: To assess iron levels in dopaminergic midbrain nuclei using quantitative susceptibility mapping for identification of biomarkers of PD. Background: The midbrain dopaminergic system plays…Effective deep brain stimulation co-modulate cross-frequency coupling
Objective: The disruption of pathological signals in the cortico-basal ganglia- network has been hypothesized as a mechanism of action of deep brain stimulation (DBS). However,…Neuronal Network Underlying Speech Difficulties in Parkinson’s Disease
Objective: We aimed to investigate whether speech difficulties are associated with changes in cortical thickness. Background: Speech difficulties are a common debilitating feature of Parkinson’s…Cortical cholinergic dysfunction correlates with microglial activation in the Substantia Innominata in patients with REM sleep behavior disorder
Objective: To explore possible correlations between levels of microglial activation (neuroinflammation) in the Substantia Innominata (SI), the major source of cholinergic input to the cortex,…Evaluation of Imidazoline 2 binding sites reflecting astroglia pathology in Huntington’s Disease: An in vivo [11C]BU99008 PET study
Objective: We aimed to evaluate the role of astroglia activation in Huntington’s disease gene expansion carriers (HDGECs) using [11C]BU99008 PET, a novel radioligand with high specificity and…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.