Generalised Polymyoclonus In a Patient With Central Nervous System Tuberculosis
Objective: Myoclonus associated with tuberculosis or following an infectious event is a transient event with an abrupt onset. It is a rare phenomenon and often…Quercetin Regulates Cadmium Induced Motor Dysfunction in Depletion of Dopamine and its Metabolites at Synapse
Objective: The present study has an attempt to understand cadmium induced alteration in dopamine and associated signaling that causes the motor alterations in rats and…Chlorogenic acid attenuates the MPTP induced apoptosis in Parkinson’s disease mouse model through pAkt signaling pathway
Objective: This study deals to investigate and explore the anti-apoptotic and molecular mechanisms of CGA in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) induced Parkinsonian mice model. Background: The debilitating…Defence Mechanism of Ego and Coping Strategy Style of the Patient with Parkinson’s Disease
Objective: To find out the prevalence of different defence mechanism and coping strategies in the patients with PD.To find out the relationship between using of…Clinical hypnosis in functional movement disorders: a potential therapeutic strategy
Objective: To present a patient with a functional movement disorder who was successfully treated with clinical hypnosis. Background: Functional movement disorders (FMD), specially fixed dystonia,…The role of stress-related genes and childhood trauma in the clinical phenotype of Functional Movement Disorders
Objective: The aim of this study was to evaluate the relationship between single nucleotide polymorphisms (SNPs) at the level of stress-related genes, childhood trauma, and…SNCA G51D missense mutation causing juvenile onset Parkinson’s disease
Objective: To report the clinical and genetic features in a Parkinson’s patient with the SNCA G51D missense mutation. Background: α-synuclein (SNCA) gene mutations are recognized…A novel intronic variant in MAPT causes FTLD-parkinsonism: Implications for regulatory mechanism of MAPT pre-mRNA splicing
Objective: To report the identification of a novel intronic variant in MAPT in a patient with familial parkinsonism-frontotemporal lobar degeneration (FTLD). Background: MAPT mutations are…GBA1 biomarkers in longitudinal CSF: GCase, Sphingolipids and alpha-synuclein
Objective: To assess the GBA1-pathway-specific biomarker profile in patient-derived CSF. Background: Heterozygous mutations in the GBA1 gene represent the most common genetic risk factor for…Sequencing of single human nigral dopaminergic neurons for somatic copy number variants
Objective: To detect somatic DNA copy number variants (CNVs) in dopaminergic neurons isolated from human substantia nigra, using shallow whole genome sequencing (WGS). Background: Somatic…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.