Investigating the impact of a-synuclein pathology on human embryonic stem cell derived dopaminergic neurons transplanted in an accelerated a-synuclein rat model of Parkinson’s disease
Objective: In this study, we assess how transplanted human embryonic stem cell (hESC) derived dopaminergic (DA) neurons survive, mature, integrate and innervate the host circuitry…REM density in isolated REM sleep without atonia
Objective: To investigate REM density in patients with isolated REM sleep without atonia. Background: Isolated RSWA (iRSWA) is regarded as a prodromal phase of REM…Treatment of dopaminergic augmented RLS with Ecopipam, A D1 specific antagonist: an exploratory placebo controlled cross-over trial
Objective: To establish initial safety and preliminary efficacy of ecopipam, a D1 specific antagonist in patients currently taking dopamine agonist and demonstrating augmentation. Background: Dopamine…What patients need – a qualitative analysis of consultations prior to deep brain stimulation in patients with Parkinson’s disease
Objective: To evaluate the different needs of patients with Parkinson’s disease (PD) prior to deep brain stimulation (DBS). Background: DBS is a well established and…Correlation between degree of dysarthria, motor severity and quality of life in patients with Parkinson’s disease
Objective: To verify the relationship between clinical findings regarding dysarthria and self-perception of PD patients. Background: Dysarthria is one of the most common non-motor symptoms…Caregiver support and its association with advanced Parkinson’s disease and clinical outcomes
Objective: To assess characteristics of advanced Parkinson’s disease (APD) patients with ongoing device-aided treatment stratified by caregiver support. Background: Observe-PD is a multicountry, cross-sectional observational…Repetitive transcranial magnetic stimulation does not improve the sequence effect in freezing of gait
Objective: To investigate the effect of repetitive transcranial magnetic stimulation (rTMS) on the sequence effect (SE) in Parkinson’s disease (PD) patients with freezing of gait…Is sprint running exercise feasible, safe and enjoyable to subjects with mild-to-moderate Parkinson’s disease?
Objective: To test the feasibility, safety, and acceptance of sprint running exercise in subjects with mild-to-moderate Parkinson’s disease (PD). Background: Positive effects of sprint running…Inflammatory cytokines in Saudi Parkinson cohort
Objective: To identify inflammatory diagnostic and prognostic biomarkers for PD in serum. Background: Parkinson's disease (PD) is the second most common neurodegenerative disorder after Alzheimer's…A review of interactive voice response systems in Parkinson’s Disease
Objective: The objective of this literature revision is to review and analyze the current research on the uses of Interactive Voice Response Systems (IVRS) in…
