Neuronal Network Underlying Speech Difficulties in Parkinson’s Disease
Objective: We aimed to investigate whether speech difficulties are associated with changes in cortical thickness. Background: Speech difficulties are a common debilitating feature of Parkinson’s…Cortical cholinergic dysfunction correlates with microglial activation in the Substantia Innominata in patients with REM sleep behavior disorder
Objective: To explore possible correlations between levels of microglial activation (neuroinflammation) in the Substantia Innominata (SI), the major source of cholinergic input to the cortex,…Evaluation of Imidazoline 2 binding sites reflecting astroglia pathology in Huntington’s Disease: An in vivo [11C]BU99008 PET study
Objective: We aimed to evaluate the role of astroglia activation in Huntington’s disease gene expansion carriers (HDGECs) using [11C]BU99008 PET, a novel radioligand with high specificity and…Park-Ease Trial: A Randomized Controlled Trial to Study the Efficacy of Exercises in Early-Stage Parkinson’s Disease
Objective: To evaluate the efficacy of exercises in early-stage Parkinson’s Disease by observing improvement in motor symptoms assessed by Unified Parkinson’s Disease Rating Scale (UPDRS)…Misdiagnosis in blepharospasm: the common imitators which should not be missed
Objective: Blepharospasm is a focal dystonia whose diagnosis is completely clinical with no blood or imaging biomarker. We observed that sometimes, patients with other disorders…Stiff-Person Syndrome and Limbic Encephalopathy Associated With GAD-antibody: A Case Report
Objective: To extend spectrum of glutamic acid decarboxylase(GAD) associated disorders by reporting a case Background: GADA associated disorders include a broad and clinically heterogeneous group…Satisfaction with care in late stage Parkinson’s disease
Objective: To assess satisfaction with care in patients with late stage Parkinson’s disease (PD) and to identify factors associated with patient satisfaction with care. Moreover,…Characterization of impulsivity in Colombian patients with Huntington’s disease
Objective: To describe impulsivity in patients with Huntington's disease using a self-report scale and through an objective test of the inhibition capacity. Describe the demographic…Comorbidities and medications in Huntington’s disease, Parkinson’s disease and the general population in a US claims database
Objective: This study characterises the comorbidities and symptoms, and treatment patterns of patients with Huntington’s disease (HD) vs patients with Parkinson’s disease (PD) vs the…Patient and physician perspectives on the care and assistance needs in Huntington’s disease
Objective: To describe the assistance needs of people with Huntington’s disease (HD) across different countries. Background: HD is a genetic, neurodegenerative and ultimately fatal disease…
