Phenotypic spectrum of Progressive Supranuclear Palsy in a Tunisian cohort
Objective: To describe the clinical and imaging features of the different phenotypes of progressive supranuclear palsy (PSP). Background: PSP is a neuropathologically defined disease entity…Deciphering the role of posttranslational modifications on α-synuclein aggregation and toxicity
Objective: The precise contribution of alpha-synuclein (ASYN) to neuronal dysfunction and death is still unclear. There is intense debate on the nature of the toxic…Longitudinal progression of spatiotemporal parameters of turning in idiopathic Parkinson’s disease patients with Freezing of Gait
Objective: To develop predictive algorithms for freezing of gait (FOG) in Parkinson’s disease (PD) using longitudinal objective assessment of turning behaviors. Background: Freezing of Gait…Cognitive impairment in patients with Parkinson’s syndrome
Objective: Study the principle of cognitive impairment in Parkinson's syndrome (brain cerebral circulation disorder, backdrop of atherosclerosis). Background: Parkinsonism-neurologic syndrome is a disorderly degenerative disease…[18F]THK-5351 PET Imaging in Progressive Supranuclear Palsy Concomitant with Cerebellar Ataxia in Early-stage: Clinicopathological Observations
Objective: To describe two cases of progressive supranuclear palsy (PSP) concomitant with cerebellar ataxia in early stage who underwent [18F]THK-5351 PET imaging and to investigate…Examining level of hemoglobin in patients with parkinson’s disease and the role of hemoglobin level in the disease course
Objective: 1. Is there a correlation between the concentration of hemoglobin in the blood and the development of Parkinson's disease? 2. Does the high level…Can the Quantified Timed Up and Go (QTUG) device support decision making for patients undergoing Deep Brain Stimulation?
Objective: To increase the speed and objectivity of decision making for patients with Parkinson’s disease and gait impairments, undergoing deep brain stimulation (DBS), using the…A study of factors causing psychiatric abnomalities in patients with Parkinson’s disease
Objective: To study the effect of disease duration , age of the patient, MOCA on neuropsychiatric manifestations in Fifty PD patients. Background: Neuro psychiatric symptoms…Serum non-mercaptalbumin as a potential biomarker in Parkinson’s disease and related disorders
Objective: To investigate the oxidized albumin ratio, which is the redox ratio of human non-mercaptalbumin (HNA) to serum albumin (HSA) (%HNA), as a biomarker in…Pramipexole regulates the depressive-like symptom through dopamine D3 not dopamine D2 receptor in a mouse model of Parkinson’s disease
Objective: The aim of this study is to understand if the antidepressant effect of pramipexole is mediated by D2R or D3R in a mouse model…
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