Non-motor symptoms in Parkinson disease motor subtypes: a study using the new MDS-NMS
Objective: To analyze the prevalence and severity of non-motor symptoms (NMS) in Parkinson disease (PD) motor subtypes (tremor-dominant, TD; postural instability/gait disorder, PIGD; and indeterminate),…Motor Networks in Tremor-Dominant Parkinson’s Disease. A resting-state functional MRI and diffusion tensor imaging analysis.
Objective: To investigate the integrity of cerebellothalamocortical circuit (CTCC) and basal ganglia-cortical loop (BGCL) connectivity in tremor-dominant PD (TD-PD) and compare with a group of akinetic-rigid…Composite UHDRS shows extensive spatial correlation with grey matter and white matter volume in Huntington’s disease gene carriers
Objective: This work sought to determine the structural correlates of variability in cUHDRS in HD gene expansion carriers (HDGC). Background: Symbol digit modalities test (SDMT),…Association of MRI-derived estimated brain age and cognitive ability in Parkinson’s disease
Objective: To characterise MRI-derived structural age-related brain health in Parkinson’s disease (PD) patients as a function of cognitive ability. Background: Normal ageing produces a stereotypical…Relationship between striatal dopamine depletion and various non-motor symptoms in non-demented patients with Parkinson’s disease: a pilot study
Objective: We aimed to investigate associations of striatal dopamine uptake and various non-motor symptoms in non-demented patients with Parkinson’s disease (PD). Background: Dopamine transporter (DAT)…Investigation of 531 cases of neuromelanin sensitive imaging, about its characteristics by disease
Objective: To investigate the utility of Neuro-Melanin sensitive MRI (NMI) by 3T MRI for diagnosis, the relationship and severity in Parkinson's disease (PD) and related…Mitochondrial Complex 1, Sigma 1 Receptor and Synaptic Vesicle protein 2A density in early de novo patients with Parkinson’s Disease: pilot PET data
Objective: In this study, we evaluated the density of Mitochondrial complex 1 (MC1), sigma 1 receptor (s1R) and Synaptic Vesicle protein 2A (SV2A) in early…Potential involvement of the caudate nucleus in GBA-associated Parkinson’s disease
Objective: Multimodal functional assessment of striatocortical loop integrity in Parkinson’s Disease (PD) patients with and without GBA variants Background: Biallelic GBA mutations provoke the lysosomal…Appropriateness of DAT Scan Ordering in a University Hospital Practice
Objective: To examine the diagnostic utility (or misuse) of DAT scanning in a University Hospital practice – is there unnecessary utilisation of DAT scanning when…Effects of exergaming on attentional deficits and dual-tasking in Parkinson’s disease
Objective: To evaluate the effects of exergaming in a controlled six week intervention trial to improve attention-based deficits and dual-tasking in PD when compared to…
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