Evaluation of Imidazoline 2 binding sites reflecting astroglia pathology in Huntington’s Disease: An in vivo [11C]BU99008 PET study
Objective: We aimed to evaluate the role of astroglia activation in Huntington’s disease gene expansion carriers (HDGECs) using [11C]BU99008 PET, a novel radioligand with high specificity and…Deep Brain Stimulation in Parkinson’s Disease: Experience of the Neurology Department of Marrakesh
Objective: The authors report the experience of the Marrakesh University Hospital in Idiopathique Parkinson's surgery. Background: The treatment ofidiopathicParkinson's disease (IPD) remains symptomatic and relies…Real World Clinical Outcomes Using a Novel Directional Lead from a Multicenter Registry of Deep Brain Stimulation for Parkinson’s Disease
Objective: In this report, initial real-world outcomes using a directional lead with a Deep Brain Stimulation (DBS) system capable of multiple independent current source control…Challenges in Parkinson’s Disease Diagnosis in a Patient with Ipsilateral Hemimelia
Objective: Our main objective is to demonstrate the challenges involved in the diagnosis of parkinsonism in a patient with transverse failure of formation of the…Freezing of Gait in Parkinson’s Disease: Risk Factors and Associated Nonmotor Symptoms
Objective: To clarify risk factors for, and clinical associations of, freezing of gait (FOG) in Parkinson's disease (PD). Background: FOG is a disabling and incompletely…Moaning: genetic analysis of a family with eight affected members
Objective: To report the clinical and genetic evaluation of a five-generation family with eight members exhibiting moaning. Background: Moaning is characterized by low-tone abnormal involuntary,…Gene Expression Profiling of depression in Huntington’s disease
Objective: This preliminary study was designed to investigate the gene expression profile by RNA-seq in HD patients with depression and without depression, and between subjects…Neuroprotective and neurotrophic efficacy of Ginkgo biloba extracts against 3-nitropropionic acid-induced oxidative stress in a rat model of Huntington’s disease
Objective: The present study examined the potential neuroprotective and neurotrophic efficacy of GBE against 3-nitropropionic acid (3-NP)-induced oxidative stress in a rat model of HD…Huntington’s Disease Protein Huntingtin Associates with its own mRNA
Objective: To investigate how Htt might affect RNA metabolism we set out to purify and analyze RNA associated with Htt. Background: The Huntington's disease (HD)…Assessment of Caregiver Burden in Huntington’s disease
Objective: We aim to identify and characterize caregiver burden among HD caregivers, to see what aspects of HD caregiving are associated with the greatest burden…
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