Genotype influences circuit compensation in Parkinson’s disease
Objective: This study investigates differences in brain network organization in patients with Parkinson’s disease (PD) with genetic risk factors relative to sporadic PD patients and…Identification and Characterization of Selective and High Affinity Small Molecules as Positron Emission Tomography (PET) Imaging Tracers for Pathological Alpha-Synuclein
Objective: The aim is to develop small molecular weight compounds which bind selectively and with high affinity to alpha-synuclein (a-syn) aggregates as diagnostic PET imaging…Mindfulness Based Stress Reduction in People with Parkinson’s Disease and their Carepartners
Objective: To assess the feasibility and impact of mindfulness based stress reduction (MBSR) on people with Parkinson’s disease (PD) and their carepartners. Background: Non-motor symptoms…Gastrointestinal symptoms as a risk factor for the appearance of motor fluctuations in patients with advanced Parkinson disease
Objective: Gastrointestinal alterations in patients with Parkinson`s Disease (EP) provoke alterations in the absorption of levodopa that facilitates the development of motor fluctuations. Study the…Four square step test in patients with early de novo Parkinson’s disease
Objective: The Four Square Step Test (FSST) is brief and easy tool to assess dynamic balance to step over hindrance. Originally developed for older adults,…Unilateral Leg Freezing in Moyamoya Syndrome
Objective: To report unilateral leg freezing in a patient with moyamoya syndrome. Background: Angiographic moyamoya is characterized by severe bilateral distal carotid stenosis with “puff-of-smoke”…Electroconvulsive Therapy (ECT): An Effective Option for the Treatment of Medication-Resistant Psychiatric Symptoms in Huntington’s Disease: A Case Series and Review of the Literature
Objective: Through a single site case series, we investigate the use and effectiveness of electroconvulsive therapy (ECT) for the treatment of refractory psychiatric symptoms in…Insomnia as clinical onset symptom in Juvenile Huntington’s Disease: Evaluation of a Family
Objective: The aim of this study to emphasize that three juvenile form of HD cases who have insomnia as clinical onset symptoms. Background: Huntington’s Disease…A global survey on speech language therapists’ awareness to Huntington’s disease
Objective: To investigate the awareness and knowledge of speech and language therapists (SLTs) on Huntington’s disease (HD) worldwide, and to explore the clinical practice and…Novel exploratory outcome assessments in GENERATION HD1
Objective: To improve collection of outcomes meaningful to patients with Huntington’s disease (HD) and their families, through the development of novel assessments of daily functional…
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