The role of Dopamine in Preparatory Inhibition: What can we learn from Parkinson’s disease?
Objective: Investigating the influence of dopamine on motor inhibition during action preparation. Background: By measuring the amplitude of motor-evoked potentials (MEPs) elicited by transcranial magnetic…Steering the Volume of Tissue Activated with Directional Deep Brain Stimulation Lead in the Globus Pallidus internus
Objective: To evaluate the effect of electrode configuration and vertical electrode spacing on volume of tissue activated (VTA) in the globus pallidus internus (GPi) with…Analysis of brain-derived blood exosomes for diagnostics of synucleinopathies
Objective: Here, we aimed to determine if measuring of α-synuclein concentration in these vesicles from oligodendrocytes and neurons can distinguish between patients with MSA or…Objective assessment of motor states in Parkinson’s disease using partial least squares and smartphone data
Objective: In this study, we will investigate the behaviour of Partial Least Squares (PLS) regression for dimension reduction and prediction of motor states of Parkinson’s…Cortical excitability in focal dystonia patients using threshold tracking technique
Objective: To investigate cortical excitability during movement compared with postural control task in healthy and focal dystonia subjects. Background: Focal dystonia is a movement disorder…To respond or not to respond to paired associative stimulation: proof of intervention by cerebello-cortical circuit
Objective: To test whether the non-responder or responder status of primary motor cortex (M1) to an LTP- inducing paired associative stimulation (PAS) protocol in healthy…Spatial distribution of functional clusters coding for reward and movement information in the striatal direct and indirect pathways
Objective: To obtain the insight how striatum processes reward based learning and motor information, we explored the responses of D1 and D2 medium spiny neurons…Oromandibular Dystonia: Clinical Data from 68 Patients
Objective: To determine the demographic and clinical data of patients with oromandibular dystonia (OMD). Background: Dystonia is a type of movement disorder characterized by sustained,…Correlation of Retinal Nerve Fiber Layer Thickness and X-Linked Dystonia Parkinsonism Measured by Spectral-Domain Optical Coherence Tomography
Objective: This is a pilot study aimed to determine the association of the Retinal Nerve Fiber Layer (RNFL) thickness with X-Linked Parkinsonism Disease patients using…Quantitative assessments better delineate rare disease: reconsidering the diagnostic criteria in ATP1A3+ Rapid-Onset Dystonia-Parkinsonism (RDP)
Objective: To revise diagnostic criteria for RDP based on a cohort of ATP1A3 mutation+ individuals. Background: RDP is caused by mutations of the ATP1A3 gene.…
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