Alpha-synuclein seeding activity in blood samples from synucleinopathy patients
Objective: Utilize a cell-based assay to determine whether a-syn seeding activity can be amplified and detected from blood components from patients with Parkinson’s disease (PD)…Levodopa Induced dyskinesia in patients with Parkinson’s disease and polymorphisms gene DRD3 dopamine receptor
Objective: The aim of this study was to investigate the association between two DRD3 gene single-nucleotide polymorphisms (SNPs) and the development of LID in patients…Initial Validation of the Cortical Basal ganglia Functional Scale (CBFS) in two international, multicenter cohorts: 4RTNI and PROSPECT
Objective: To assess the validity of a patient/caregiver-reported scale for assessing functional disability in 4R tauopathies. Background: 4R tauopathies (4RT) including progressive supranuclear palsy (PSP),…“UPDRS-meter” – a digital and automatic UPDRS scoring application
Objective: To assess the feasibility of a smartphone-based application for performing a motor test that will provide an accurate UPDRS score. Background: Parkinson’s Disease (PD)…Blood–brain barrier breakdown in an adult mouse model of Parkinson’s disease
Objective: This study aims to evaluate the integrity of the blood-brain barrier (BBB) in parkinsonism. Background: Parkinson's disease (PD) is a neurodegenerative disorder which is…Shuffling gait may be pitfall in neurological examination in Parkinson’s disease
Objective: The purpose of this study is to investigate the gait in early stage of PD who did not complain of gait disturbance using three-dimensional…Phenotypic variability and extreme age of presentation of GCH1 gene mutation in dopa-responsive dystonia
Objective: To highlight the wide phenotypical variability among GCH1 gene mutation carriers and the importance of molecular work-up and establishing genotype-phenotype correlations in GCH1 related…Cortical Homeostatic Plasticity Alteration in Cervical Dystonia
Objective: To investigate the link between sleep and cortical plasticity in cervical dystonia (CD). Background: CD is the most frequent type of dystonia. Although still…Postural Abnormalities in Parkinson’s Disease: an Epidemiological and Clinical Multicenter Study
Objective: To evaluate the overall prevalence of postural abnormalities (PA) in patients with Parkinson’s disease (PD) and to assess their association with demographic and clinical…Predictors of quality of life in dystonia – a longitudinal study
Objective: To determine the impact of physical and psychiatric morbidity on health-related quality of life (HR-QoL) in a large, international, multi-centre cohort of isolated dystonia…
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