Differential diagnosis of Parkinsonian Syndromes – combining clinical and imaging data in a machine-learning approach
Objective: To assess the feasibility of automated classification of different parkinsonian subtypes using clinical and imaging variables in a single center study. Background: The clinical…Age-related failure in compensatory mechanisms and its relation to the Parkinson phenotype: evidence from a SPECT study in early and late-onset PD
Objective: To investigate if a less prominent dopaminergic dysfunction on 123I-ioflupane SPECT imaging (DaTSCAN) despite a more severe motor phenotype in Late Onset Parkinson’s Disease…Dual-task in Parkinson’s disease: a gait analysis and functional MRI study
Objective: To study gait parameters and functional MRI (fMRI) patterns performing dual-task in Parkinson’s disease patients with postural instability and gait disorders phenotype (PD-PIGD) and…White matter and subcortical volume of essential tremor patient decreases after MR-guided focused ultrasound thalamotomy
Objective: To study the anatomic volume differences of essential tremor (ET) patient before and after MR-guided focused ultrasound (MRgFUS) thalamotomy using respective 3D T1-weighted MR…Kick Out PD: Mobility, Quality of Life, and Feasibility Outcomes in a Pilot Study of a PD-Specific Karate Intervention
Objective: To evaluate feasibility of a community-based karate class tailored for individuals with early- to middle-stage Parkinson’s Disease (PD); to assess effect of karate on…ATP1A3 Gene Mutations Associated With Rapid-Onset Dystonia-Parkinsonism (RDP) Presenting As Functional Neurologic Disorder: A Report of Two Cases
Objective: Functional neurologic disorder (FND) diagnostic criteria continues to evolve, with current emphasis on positive neurologic signs, including sudden onset, inconsistency or incongruence, without reliance…Postural Instability Assessed by Static and Dynamic Posturography in the Early Stage of Parkinson’s Disease
Objective: The early stage of Parkinson’s disease (PD) (Hoehn-Yahr (HY) I-II stages) is characterized by a negative pull test, which clinically excludes postural instability. Previous…Paresthesia and gait impairment in a patient with advanced Parkinson disease-case report
Objective: Our main objective is to illustrate different etiologies for paresthesia and gait impairment that can occur in a patient with Parkinson disease. We present…Clinimetric properties of direct contemporaneous FOG score rating
Objective: To determine the clinimetric properties of the direct rating of the Freezing of Gait (FOG) score compared to the off-line rating from video recordings.…Homozygous Huntington’s disease with two reduced penetrance alleles: A Case Report
Objective: To clinically characterize a Huntington's disease patient with two reduced penetrance alleles. Background: Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder manifesting with…
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