Technology-based assessment of motor impairment in de novo Parkinson’s disease patients: implications for diagnostic accuracy and early identification of distinct phenotypes
Objective: 1. To study motor functions in de novo drug-free Parkinson's disease (PD) patients and healthy controls (HC) and find an algorithm able to distinguish…MDS Translation Program for MDS-UPDRS and UDysRS
Objective: To summarize the status of the MDS-sponsored translation programs for non-English versions of the MDS-UPDRS and UDysRS. Background: The MDS-UPDRS and UDysRS were developed…Visual evoked potentials alterations in DLB
Objective: To investigate whether DLB and PD patients show VEP and OCT alterations in comparison with AD patients, and whether this possible alterations are associated…Tsallis entropy of EEG correlates with future cognitive decline in patients with Parkinson’s disease
Objective: To evaluate whether Tsallis entropy (TE) constitutes a possible functional characterization of neurodegeneration and a measure to predict progression of Parkinson’s disease (PD). Background:…Unilateral increase of blink reflex recovery cycle in drug-naive hemiparkinson syndrome.
Objective: We assessed R2 Blink Reflex Recovery Cycle (R2 BRRC) in drug-naive Parkinson’s disease (PD) patients with unilateral tremor and/or rigidity, diagnosed as hemiparkinson syndrome,…Depression and cognitive impairment in isolated focal-onset dystonia: prevalence and risk factors in a group of Romanian patients
Objective: To assess the prevalence of depression and cognitive impairment and their potential risk factors in a group of Romanian patients with isolated focal-onset dystonia…Efficacy and Safety of AbobotulinumtoxinA in Adults with Cervical Dystonia: Similar Results Between 1mL and 2mL Dilution Methods
Objective: To evaluate efficacy and safety of a single injection of abobotulinumtoxinA using 1-mL or 2-mL dilution in adults with CD. Background: AbobotulinumtoxinA is approved…RDP is associated with bulbar and limb weakness: broadening the phenotype of ATP1A3+ Rapid-Onset Dystonia-Parkinsonism (RDP)
Objective: To describe a new finding of weakness associated with RDP. Background: RDP is caused by mutations of the ATP1A3 gene. The phenotype of RDP…Genotype-phenotype relations for the isolated Dystonia Genes TOR1A, THAP1, GNAL, ANO3, KMT2B, PRKRA and HPCA: MDSGene Systematic Review
Objective: To systematically review genotypes and phenotypes of monogenic isolated dystonia. Background: The Movement Disorder Society Genetic mutation database (MDSGene at www.mdsgene.org) provides an overview…Neuromuscular electrical stimulation for the treatment of jaw-closing dystonia
Objective: To measure whether neuromuscular electrical stimulation (NMES) increases jaw-opening distance and improves quality-of-life in jaw-closing dystonia patients. Background: An index case with progressive supranuclear…
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