The role of Parkinson’s disease-associated RHOT1/Miro1 variants in mitochondrial dysfunction and impaired cellular quality control
Objective: In the present study we intent to investigate the effect of mutant Miro1 proteins on mitochondrial function and cellular quality control mechanisms in iPSC-derived…Cerebellar transcranial magnetic stimulation with neuronavigation for postural instability in PSP
Objective: We created a TMS protocol for paired-pulse cerebellar-M1 stimulation and repetitive cerebellar stimulation to augment cerebellar-brain inhibition and reduce postural instability in progressive supranuclear…Synaptic function in Parkinson’s disease associated with GBA mutations
Objective: To investigate the pathological substrate of impaired cognition in Parkinson’s disease (PD) associated with glucocerebrosidase (GBA) mutation. Background: Mutations in glucocerebrosidase gene (GBA), originally…Clinical patterns of gait freezing in Parkinson’s disease and their response to interventions: an observer-blinded study
Objective: To evaluate the occurrence and severity of FOG in provoking situations during a standard video-recorded walking task. To use this method to compare the effects…The effect of coexistent neurodegenerative disorders on the clinical features of idiopathic normal pressure hydrocephalus
Objective: To determine the prevalence of neurodegenerative disorders in idiopathic normal pressure hydrocephalus (iNPH) and their effects on the clinical features of iNPH. Background: To…Baseline hyposmia and RBD symptoms are associated with faster, but differential, cognitive decline at 2 years in the PPMI study
Objective: To explore the potential role of baseline hyposmia and RBD symptoms on progression of cognitive decline at 2 years. Background: Cognitive decline in PD…Zonisamide ameliorates levodopa-induced dyskinesia via striatal cholinergic system in a rat model of Parkinson’s disease
Objective: To investigate the difference in results according to the mode of levodopa administration and the effect of zonisamide (ZNS) on striatal cholinergic system, we…Cognitive event related potentials as biomarker of non-motor phenotypes in Parkinson’s Disease
Objective: This research aimed to study the specific changes in cognitive event related potentials (ERP) in patients with different non-motor subtypes of Parkinson’s disease (PD).…STN-DBS programing for dyskinesia: a case report
Objective: To investigate the effect of STN stimulation on different types of dyskinesia and programming strategy. Background: Long-term use of levodopa or dopamine agonists often…Machine learning classifiers and subjective vocal perception of Parkinson’s disease patients and healthy control
Objective: To identify machine learning classifiers and to assess the acoustic differences between PD patients and healthy control (HC) and the relations between objective and…
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