The Genetic Landscape of Complex Childhood-Onset Hyperkinetic Movement Disorders
Objective: To better delineate the genetic landscape and key clinical characteristics that define complex early onset monogenic hyperkinetic movement disorders (HMD). Background: Hyperkinetic movement disorders…Validation of the Clinical Dementia Rating Scale Sum of Boxes in Parkinson’s Disease
Objective: To assess the psychometric properties of the Clinical Dementia Rating Scale Sum of Boxes (CDR-SOB) in Parkinson’s disease (PD) across levels of cognitive abilities.…Motor intracortical excitability before speech onset in adults who stutter
Objective: A core feature of persistent developmental stuttering is the paroxysmal, transient, involuntary loss of speech motor control. However, the neurophysiology of stuttering remains largely…Continuous levodopa- carbidopa gel recovers motor cortex plasticity in advanced Parkinson’s disease
Objective: The objective of this study was to investigate if continuous infusion of levodopa- carbidopa gel (LCIG) improves motor complications of Parkinson's disease (PD) and…Changes of cutaneous and cortical silent responses in a random sample of Lithuania patients with Parkinson disease
Objective: To investigate the properties of central and peripheral innervation in Parkinson disease (PD) using transcranial magnetic stimulation (TMS) and electroneurography (ENG), also to evaluate…Acupuncture as Adjuvant Therapy for the Management of Cervical Dystonia
Objective: We conducted a pilot open-label study of acupuncture treatments as add-on therapy to botulinum toxin injection sessions (three months apart) in five subjects with…Botulinum toxin for the management of dystonic scoliosis in children
Objective: To report the use of botulinum toxin (BoNT) for the treatment of dystonic scoliosis in children with cerebral palsy. Background: Children with CP and…Abnormal Sensorimotor Processing in Cervical Dystonia in Functional Magnetic Resonance Imaging
Objective: The aim of this study was to assess brain activation during voluntary sequential finger tapping in cervical dystonia patients while manipulating task complexity. Background: Cervical dystonia…Pediatric Deep Brain Stimulation in Secondary Dystonia using Stereotactic Depth Electrode Targeting
Objective: The primary objective of our pediatric clinical research is to improve outcomes after deep brain stimulation for pediatric patients with secondary dystonia. We apply…Evaluating Multimodal Integration of Abnormalities in Adult Onset Idiopathic Focal Dystonia (AOIFD) via Multivariate Pattern Analysis (MVPA) and Ensemble Learning (EL)
Objective: Investigate MVPA and EL for understanding the relationship between structural and functional abnormalities in AOIFD. Background: AOIFD is a movement disorder with diverse phenotypes…
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