Different patterns of brain activity during lower limb movements in Parkinson’s disease patients with and without freezing of gait
Objective: To assess brain functional MRI (fMRI) activity during a feet movement task in Parkinson’s disease patients with (PD-FoG) and without freezing of gait (PD-noFoG)…Functional connectivity within the cerebellum and brainstem in essential tremor patients– a tailored resting state fMRI approach
Objective: To better understand the pathophysiology of essential tremor (ET) by analysing brainstem and cerebellar neuronal circuitry activity with tailored fMRI resting state methods. Background:…Neuroimaging in Parkinson’s disease dementia: Connecting the dots
Objective: To identify the neural substrates of Parkinson’s disease dementia (PDD) and Parkinson’s disease with Mild Cognitive Impairment (PD-MCI) using a network mapping approach. Background:…Blue light therapy glasses in Parkinson’s disease: patients’ experience and effectiveness
Objective: We aimed to assess how patients experience the use of blue light glasses, a novel way of delivering light therapy, aiming to optimise compliance…Autonomic features in E46K-SNCA carriers
Objective: To evaluate structural and functional integrity of small autonomic nerve fibers and phosphorylated alpha-synuclein (p-syn) deposition in the skin of E46K-SNCA carriers as compared…Are we underestimating the dysautonomic burden in GBA related a-synucleinopathies?
Objective: The aim of the present study is to understand the prevalence of dysautonomic symptoms in a cohort of Italian glucocerebrosidase (GBA) mutated patients with…Clinical Management of Incipient Wearing-off with the 19-Items Wearing off Questionnaire (WOQ-19)
Objective: To evaluate the use of the 19-items Wearing off Questionnaire (WOQ-19) to detect fluctuations in patients with non-advanced Parkinson's disease (PD) and to evaluate…Can we hear pathology in premanifest Huntington’s disease? Acoustic and listener-based analysis of speech
Objective: The present study evaluated the ability of acoustic and listener-based perceptual measures to differentiate speech deficits in the premanifest and early stages of HD…The Roche HD Natural History Study – an external comparator by design
Objective: The Roche Natural History (NH) study in Huntington’s disease (HD) (NCT03664804) is a prospective, longitudinal cohort study designed to provide further clinical validation of…Burden of Huntington’s disease in the US: Analysis of an insured population
Objective: To describe the healthcare resource utilization (HRU) in Huntington’s disease (HD) in private (commercial) and public (Medicare and Medicaid) insurance plans in the US.…
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