Mandibular Advancement Device in Parkinson’s disease: an efficacious and usable device in a disabling disease
Objective: The aim of our study is to explore the efficacy, observance, and usability of Mandibular Advancement Device in patients with Parkinson’s disease (PD) and…A Dual-Center Study of Pain and Other Non-motor Symptoms in Parkinson disease
Objective: This study aims to explore the relationship between pain and other non-motor symptoms in Parkinson Disease (PD). Background: Pain is a common non-motor symptom…A Prospective Study of the Effects of Deep Brain Stimulation on Constipation and Olfaction in Parkinson Disease
Objective: To investigate the effects of subthalamic nucleus deep brain stimulation (STN-DBS) on constipation and olfaction in patients with Parkinson disease (PD). Background: STN-DBS is…A Comparative Study of Measured and Predicted Metrics of Respiratory Function in People with Parkinson’s Disease (PD)
Objective: The objective of this research was to compare measured metrics of respiratory function – Spirometry, Respiratory Muscle Strength and Peak Cough Flow – with…Clinical correlation between 99mTc-TRODAT-1 SPECT and parkinsonism
Objective: Correlate the clinical parkinsonism and TRODAT. Background: 99mTc-TRODAT-1 SPECT is well documented method for dopamine transporter survey. Clinical use was usually for Parkinsonism in…Relative Preservation of Serotonergic Function Increases Response to Treatment in Early PD
Objective: To investigate interactions between the serotonergic and dopaminergic systems in early PD as related to (i) response to treatment and (ii) dopamine (DA) release,…Fractional anisotropy patterns in non-demented Parkinson’s disease patients using hierarchical cluster analysis
Objective: We aim to characterize PD subtypes using a hypothesis-free, data driven approach based on fractional anisotropy (FA) measures. Background: Clinical variability in the Parkinson’s…Is awake physiological confirmation necessary for DBS treatment of Parkinson’s disease today? A comparison of intraoperative imaging, physiology, and physiology imaging-guided DBS in the past decade
Objective: To comprehensively compare the use of IMG-DBS, PHY-DBS and COMB-DBS in treating PD. Background: Deep brain stimulation (DBS) is a well-established surgical therapy for…Relationship between symptoms and regional density of metabotropic glutamate receptors subtype 1 measured with 11C-ITMM PET in de novo Parkinson’s disease
Objective: To investigate correlations of motor and non-motor symptoms with the brain densitiesof the metabotropic glutamate receptor subtype 1 (mGluR1) in de novo Parkinson’s disease…Extrastriatal dopaminergic and serotonergic pathways in Parkinson’s disease and in dementia with Lewy bodies: a 123I-FP-CIT study
Objective: To evaluate the common and divergent dopaminergic and serotonergic impairment in Parkinson's disease and dementia with Lewy bodies using 123I-FP-CIT imaging. Background: Striatal dopaminergic…
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