A Thorough QT Study of Apomorphine Sublingual Film in Patients With Parkinson’s Disease Complicated By “OFF” Episodes
Objective: To assess the effect of apomorphine sublingual film (APL130277; APL) on the QT interval in patients with Parkinson’s disease (PD) and “OFF” episodes participating…Identification of potential new genes involved in autosomal recessive forms of Parkinson’s disease
Objective: The aim of the work is to identify new genes involved in autosomal recessive (AR) early-onset (EO, >40 years) Parkinson disease (PD), using consanguineous…Lip movement contribution in speech production of persons with Parkinson’s Disease
Objective: Lip movements contribute to communication by producing labial sounds, conveying facial expression and aiding visually in speech perception. This study planned to understand lip-movements…The Impact of Progressive Supranuclear Palsy (PSP) Disease Severity on Healthcare Resource Utilization (HCRU)
Objective: To measure the impact of PSP disease severity on HCRU in a real-world setting. Background: PSP is a neurodegenerative disease. As it progresses, patients’…The Chinese Parkinson’s disease Registry scheme
Objective: This large prospective longitudinal cohort aims to identify nature history of a highly-presentative Chinese PD population and to discern clinical and genetic markers which…Motor-based assessment of prodromal Parkinson’s disease combining wearable sensors and machine learning
Objective: To provide the neurologist with a decision support system based on inertial sensors and learning algorithms for an objective early diagnosis of Parkinson’s disease…Validation of the Hebrew version of the Unified Dyskinesia Rating Scale (UDysRS)
Objective: To assess the clinimetric properties of the Hebrew version of the UDysRS. Background: Dyskinesia is a common side effect of dopaminergic treatments for Parkinson's…Impaired intracortical inhibition predicts response to medication in Parkinson’s disease patients
Objective: To check whether measures of motor cortex excitability and plasticity are associated with clinical response to dopaminergic treatment in Parkinson’s disease (PD) patients. Background:…Characterising the role of alpha-synuclein in ferroptotic programmed cell death in the context of Parkinson’s Disease
Objective: Despite the involvement of alpha synuclein (α-syn) pathology in Parkinson's disease (PD) pathology, the consequences on the neuropathology and the type of programmed cell…Comparison of LFP-physiomarkers for DBS programming
Objective: To evaluate clinical usability of LFP(local field potentials)-physiomarkers and lead localisation for selection of suitable DBS electrode configurations. Background: Selection of optimal contacts in…
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