Exploring the relationship between motor and non-motor fluctuations in Parkinson’s disease: patient’s perspective, clinician’ s assessment and objective measures from a wearable device
Objective: We aimed: 1) To evaluate the relationship between motor (MF) and non-motor (NMF) fluctuations in Parkinson’s disease measured with patient’s self-assessment, clinician’s evaluationand objective measurement using a wearable…Whole-Body Neuromuscular Ultrasound for Evaluating Posture and Targeted Management of Muscle Spasticity and Pain
Objective: The aim was to assess efficacy of whole body neuromuscular ultrasound to evaluate posture and targeted management of muscle spasticity and pain. Background: Muscle…Functional brain connectome in drug-naïve Parkinson’s disease patients
Objective: To investigate whole-brain network topologic organization in a large cohort of drug-naïve Parkinson’s disease (PD) patients using resting-state functional MRI (rs-fMRI); and to determine…Functional MRI activation during the Symbol Digit Modalities Test in Parkinson’s disease
Objective: To assess alterations in functional brain activation patterns related to mental slowing in patients with Parkinson’s disease (PD). Background: Attentional deficits, namely mental slowing,…Glymphatic system activity in Parkinson’s disease: diffusion tensor image analysis along the perivascular space (DTI‑ALPS)
Objective: We examined the activity of the glymphatic system in patients with Parkinson’s disease using diffusion tensor image analysis along the perivascular space (DTI-ALPS). Background:…The Use of Diffusion Weighted Imaging to Detect Structural Biomarkers in Recently-Diagnosed Parkinson’s Disease Patients
Objective: To quantify biomarkers for recently-diagnosed PD patients in the midbrain and their dopaminergic connections to the striatum. Background: The development of improved PD treatments…FDG PET: a good predictive tool for CNS inflammation
Objective: 1)When to suspect an underlying autoimmune process in patients presenting with parkinsonism. 2)To highlight the importance of FDG PET as a complementary exam in…NEURONAL NETWORK UNDERLYING DYSPHAGIA IN PARKINSON’S DISEASE
Objective: We aimed to investigate whether chewing and swallowing difficulties are associated with changes in cortical thickness. Background: Chewing and swallowing difficulties are a common…Amyloid load and cognitive decline in Parkinson’s disease: preliminary longitudinal findings
Objective: To test for any association between amyloid deposition and future cognition in Parkinson’s disease, in a sample enriched for mild cognitive impairment. Background: Progressive…The role of Synaptic vesicle protein 2A (SV2A) in patients with Parkinson’s disease dementia and Dementia with Lewy bodies: An in vivo [11C]UCB-J PET study
Objective: We aimed to investigate the role of synaptic vesicle glycoprotein 2A (SV2A) in Parkinson’s disease dementia (PDD) and Dementia with Lewy bodies (DLB) using…
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