Effects of exergaming on attentional deficits and dual-tasking in Parkinson’s disease
Objective: To evaluate the effects of exergaming in a controlled six week intervention trial to improve attention-based deficits and dual-tasking in PD when compared to…Assessing the validity and reliability of MANAGE-PD tool to identify patients with Parkinson’s disease inadequately controlled on oral medications – Results from an international survey of general neurologists and movement disorder specialists
Objective: To evaluate the validity and reliability of MANAGE-PD tool. Background: Timely identification of advancing symptoms in patients with Parkinson’s Disease (PD), thereby improving opportunities…Arm levitation as an early manifestation in MELAS syndrome: A case report
Objective: Arm levitation in MELAS syndrome Background: MELAS syndrome has broad manifestations including stroke-like episodes, dementia, epilepsy, lactic academia, myopathy, recurrent headaches, hearing impairment, diabetes and short…Impulse control and repetitive behavior disorders are more common in PD patients with levodopa-induced dyskinesias
Objective: Our aim was to evaluate the prevalence of impulse control and repetitive behavior disorders (ICRB) in patients affected by Parkinson's disease (PD) with and without levodopa-induced…Adult-onset stereotypy — An atypical presentation of frontotemporal dementia
Objective: Describe a case of adult-onset stereotypy with abulia. Background: Stereotypy is a non-goal directed but distractible behavior repeated continuously. While common in the pediatric…Translating Preclinical Data to a Human Equivalent Dose for AMT-130 AAV Gene Therapy for Early Manifest Huntington’s Disease
Objective: To extrapolate the human equivalent dose (HED) for a Phase I/II clinical trial in adults to explore the safety, tolerability, and efficacy of striatally-administered…Prevalence of Huntington’s Disease in Sardinia, Italy
Objective: We have performed a service-based epidemiological analysis extended to the population residing in Sardinia. The socio-cultural isolation of this large Mediterranean island makes genetic…Usefulness of Heart Rate Variability to Identify the Risk of Falling in Huntington’s Disease
Objective: To evaluate the relationship between the HRV and the risk of falling in HD patients. Background: Huntington's disease (HD) patients have a high prevalence…Parkinson Kinetigraph – does it change the management of PD patients?
Objective: This pragmatic randomized open trial evaluated if the information from a Parkinson Kinetigraph (PKG) recording changed the management of PD patients at a visit…Incidence of treatment-emergent adverse events in Parkinson’s disease patients according to baseline disease severity: post-hoc analysis from double-blind combined BIPARK-I and II data
Objective: To evaluate the incidence of treatment-emergent adverse events (TEAEs) in levodopa-treated Parkinson’s Disease (PD) patients with motor fluctuations and taking opicapone (OPC). Background: OPC…
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