Brain amyloid contribution to cognitive dysfunction in Lewy bodies disorders: a pilot study
Objective: To investigate regional [18F]florbetapir binding to amyloid-β and its contribution to cognitive dysfunction in Lewy bodies disorders. Background: Lewy bodies disorders like Parkinson’s disease…The Promise of Automation: Development and preliminary testing of a language-based machine learning algorithm in PD
Objective: The proposed work seeks to expand current machine learning algorithms in PD using both motor and language features to discriminate affected speakers from healthy…Cognitive ability characterization of rat model with mutated alpha-synuclein overexpression
Objective: The present study aims to assess cognitive function in a rat model of mutated alpha-synuclein overexpression in order to determine whether this model can…The interplay between cholinergic activity, attention, and turning in Parkinson’s disease
Objective: Explore how cholinergic activity (measured by short latency afferent inhibition [SAI]) and attention relate to quality of turning performance over a week of daily…The utility of DCTclock™ (the digital clock drawing test) for unmasking early cognitive decline in Parkinson’s disease
Objective: To examine the utility of DCTclock, for assessing subtle cognitive impairments in early Parkinson's disease (PD). Background: The identification of cognitive decline is crucial…Accuracy of the MoCA in Detecting PD-MCI in the Ontario Neurodegenerative Disease Research Initiative study
Objective: To investigate the ability of the Montreal Cognitive Assessment (MoCA) to detect mild cognitive impairment (MCI) in Parkinson’s disease (PD) using variations in cognitive…RNA binding protein mediated regulation of striatal transcriptome in Parkinson’s disease.
Objective: To investigate the role of RNA binding protein Elavl in Parkinson’s disease related adaptive changes in the striatal transcriptome. Background: Elav-like (Elavl or Hu)…Weighting fibroblasts for future diagnostic prospect
Objective: To determine the dry mass of fibroblasts obtained from apparently healthy individuals and patients with brain disorders or cancer pathologies for future diagnosis prospect.…Advanced Stage of Parkinson’s Disease: From Identification to Characterization and Disease Burden Assessment Using a Nationwide Database
Objective: To identify and describe PD patients who were prescribed intensified therapy and compare their burden of disease with mild-moderate PD patients. Background: Real-world data…Gender-dependent improvement in the survival of Parkinson’s disease patients in Finland
Objective: To longitudinally investigate the overall survival (OS) of a large cohort of Parkinson's disease (PD) patients. Background: While there is evidence of increasing incidence,…
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