Dynamic functional connectivity signature of cognitive decline in Parkinson’s disease
Objective: Aim of the present study was to characterize the dynamic changes of functional connectivity associated with Parkinson’s disease (PD) cognitive decline using dynamic functional…Fractional anisotropy patterns in non-demented Parkinson’s disease patients using hierarchical cluster analysis
Objective: We aim to characterize PD subtypes using a hypothesis-free, data driven approach based on fractional anisotropy (FA) measures. Background: Clinical variability in the Parkinson’s…Is awake physiological confirmation necessary for DBS treatment of Parkinson’s disease today? A comparison of intraoperative imaging, physiology, and physiology imaging-guided DBS in the past decade
Objective: To comprehensively compare the use of IMG-DBS, PHY-DBS and COMB-DBS in treating PD. Background: Deep brain stimulation (DBS) is a well-established surgical therapy for…Relationship between symptoms and regional density of metabotropic glutamate receptors subtype 1 measured with 11C-ITMM PET in de novo Parkinson’s disease
Objective: To investigate correlations of motor and non-motor symptoms with the brain densitiesof the metabotropic glutamate receptor subtype 1 (mGluR1) in de novo Parkinson’s disease…Extrastriatal dopaminergic and serotonergic pathways in Parkinson’s disease and in dementia with Lewy bodies: a 123I-FP-CIT study
Objective: To evaluate the common and divergent dopaminergic and serotonergic impairment in Parkinson's disease and dementia with Lewy bodies using 123I-FP-CIT imaging. Background: Striatal dopaminergic…Sleep Disturbances in Essential Tremor: A pilot investigation of the related brain microstructural changes using diffusion tensor imaging
Objective: In this pilot exploratory study, we aimed to search possible related brain microstructural changes of sleep disturbances (SD) in essential tremor (ET) patients. Background:…The Dutch Parkinson and Cognition study (DUPARC): Cognitive impairment and cholinergic innervation in de novo Parkinson’s Disease patients
Objective: To explore the incidence and characteristics of early cognitive impairment in Parkinson’s disease (PD) patients and the relationship with regional cholinergic innervation. Background: Cognitive…Transcranial Photobiomodulation as an adjunct to Levodopa therapy in patients with Parkinson’s Disease; an open label pilot study
Objective: To explore the effects of transcranial Photobiomodulation (tPBM) on symptoms of Parkinson's Disease and establish this therapy's efficacy as an adjunct to Levodopa. Background:…Large Sample Study on Paroxysmal Kinesigenic Dyskinesia: Genotype-Phenotype Analysis and Diagnosis Recommendations
Objective: By analyzing nationwide large samples provided by China Paroxysmal Kinesigenic Dyskinesia Association(CPKDA), this study is attempted to summarize the clinical phenotypes and genetic features…Quantifying gait parameters in Parkinson’s disease patients who do and do not exhibit freezing of gait.
Objective: To determine whether gait parameters in PD patients who have freezing of gait (FOG) differ from those who do not. Background: FOG is a…
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