Targeted Next Generation Sequencing in Diagnosis of Dystonia Patients
Objective: To assess the effectiveness of the targeted next generation sequencing in dystonia patients in China. Background: Dystonia is a movement disorder with high clinical…Expanding the clinical phenotype of autosomal recessive spinocerebellar ataxia with Adult onset; a collection of case series
Objective: We present a case series of adult onset ataxia with variability in genetic mutations, yet common clinical phenotypic presentations that constitute the autosomal recessive…Preliminary evidence for an altered relationship between uric acid levels and resting state functional connectivity in REM sleep behavior disorder
Objective: To determine the relationship between uric acid (UA) levels and functional connectivity in REM sleep behavior disorder (RBD) compared to controls. Background: UA levels…Superior cerebellar peduncles atrophy of PSP on PADRE imaging; comparison with idiopathic PD
Objective: The purpose of our study was to determine whether atrophy of Superior cerebellar peduncles (SCP) on phase-weighted magnetic resonance imaging technique (PADRE) was useful…Neuromodulatory properties of flavonoids from Persea americana Peel: Role in CNS redox homeostasis and neurobehavioral markers
Objective: Isolating flavonoids from Peel of Persea americana fruits & testing their effects on CNS redox homeostasis culminating in neurobehavioural amelioration among rats. Background: Cellular…Bereitschaftspotential in a Patient with Functional Propriospinal Myoclonus
Objective: To illustrate the presence and characteristics of functional propriospinal myoclonus with Bereitschaftspotential (BP). Background: The etiology of propriospinal myoclonus is mostly uncertain and functional…Final Safety Results of EASE LID 2 Study: Long Term Open-Label Study of ADS-5102 for Dyskinesia in Parkinson’s disease (PD) patients
Objective: The primary objective of this study was the safety and tolerability of ADS-5102 in PD patients with dyskinesia. Secondary efficacy outcome measures included MDS-UPDRS,…Dyskinesia management in COMT-naïve patients starting adjunctive therapy with opicapone: The BIPARK-I double-blind experience
Objective: To elucidate which levodopa-treated COMT-naïve Parkinson’s Disease (PD) patients were at higher risk for developing dyskinesia when starting opicapone (OPC) 50mg or entacapone (ENT).…Exploring the utility of the ChulaPD intelligent Parkinson’s disease car to determine naturalistic driving ability in Parkinson’s disease patients: A pilot study of 10 patients
Objective: To examine the naturalistic driving performance in PD patients compared to controls and to determine if the PD patients showed diminished abilities. Background: Competence…The Interface of advanced therapies as Parkinson’s disease progresses – case reports
Objective: To explore the practical benefits and challenges of adding duodenal levodopa-carbidopa intestinal gel infusion (LCIG) to subthalamic nucleus deep brain stimulation (STN DBS) in…
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