The correlation studies between cholinergic cognitive impairment of Parkinson’s disease and the cortex thickness of brain
Objective: To determine whether cognitive domain impairment of visuospatial, memory, attention is related to dysfunction of brain cholinergic neurotransmitter system in mild cognitive impairment of…A study of correlation between screening tools for cognitive decline and gait status using three-dimensional gait analysis
Objective: The objective of this study is to evaluate the correlation between screening tool for dementia and gait status. Background: Gait impairment in patient with…Mild to moderate dyskinesia is not significantly related to the level of activity engagement or quality of life of patients with Parkinson’s disease
Objective: This cross-sectional study aimed at determining the relation between levels of drug-induced dyskinesia (DID), tremor, rigidity, bradykinesia, postural instability, as well as cognition and…Future doctors as health educators: Undergraduate medical students raise awareness and unite for Parkinson’s disease
Objective: To highlight the role of undergraduate students in raising the awareness about Parkinson's disease among peers and public. Encouraging the students to take responsibility…The establishment of Deep Brain Stimulation Nurse Association (DBSNA) in United Kingdom (UK)
Objective: This is a qualitative analysis in the establishment of DBSNA for specialist nurses working in neuromodulation in the UK. Background: Surgical movement disorder nurses…Intronic pentanucleotide TTTCA repeat insertion in SAMD12 gene causes familial cortical myoclonic tremor with epilepsy type 1
Objective: To identify the causative mutation in pedigrees with familial cortical myoclonic tremor with epilepsy (FCMTE) type 1. Background: FCMTE is an autosomal dominant neurodegenerative…New Nomenclature Of Genetic Myoclonus Syndromes
Objective: In collaboration with the International Parkinson and Movement Disorder Task Force for Nomenclature of Genetic Movement Disorders, we present a new classification of genetically…Exploring the neural correlates of gait asymmetry in idiopathic REM Sleep Behaviour Disorder
Objective: Given the typical asymmetric onset of motor symptoms in PD, the current study sought to investigate whether patients with iRBD show evidence of asymmetric…Safinamide inhibition of in vivo glutamate release in a rat model of Parkinson’s Disease
Objective: To evaluate whether safinamide inhibits in vivo glutamate (Glu) release in a rodent model of Parkinson’s disease (PD), i.e. the 6-hydroxydopamine (6-OHDA) hemilesioned rat.…The Small Molecule Alpha-Synuclein Misfolding Inhibitor, NPT200-11, Produces Multiple Benefits in an Animal Model of Parkinson’s Disease
Objective: To evaluate effects of NPT200-11 on Parkinson’s disease (PD)-relevant outcomes including alpha-synuclein pathology, neurodegenerative markers and motor performance in transgenic mouse models of PD.…
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