Duration of response with abobotulinumtoxinA in cervical dystonia: Patient distribution results from two open label extension studies
Objective: To report patient distribution data for duration of response with abobotulinumtoxinA (aboBoNT-A; Dysport®) from two open-label (OL) studies in patients with cervical dystonia (CD).…Physiological effects of Botulinum Toxin therapy in Primary Cervical Dystonia
Objective: To examine the physiological effects of botulinum toxin (BoNT) therapy, as measured by paired-pulse transcranial magnetic stimulation (TMS), in patients with primary cervical dystonia…Abnormal cerebellar learning in cervical dystonia
Objective: This study was conceptualized to asses if patients with cervical dystonia (CD) exhibit deficits in cerebellar function tested by motor adaptation and motor sequence…Neuropathology of dopa-responsive dystonia due to Tyrosine hydroxylase deficiency
Objective: To describe detailed neuropathology findings from an autopsy case of dopa-responsive dystonia (DRD) with genetically confirmed tyrosine hydroxylase deficiency (THD). Background: DRD comprises a…Underserved Patient Access to Movement Disorders Care: Experience from a Tertiary Academic Referral Center
Objective: To explore geographical and clinic-demographical profile of underserved patients in Florida diagnosed with movement disorders. Background: Movement disorders are complex conditions that often require…Prediction of suicidality in Huntington disease: Analysis of Enroll-HD data using machine learning approach
Objective: To develop a model for prediction of suicidal ideation or suicidal behaviour in Huntington disease gene expansion carriers (HDGEC) based on Enroll-HD data using…Comparing risperidone and olanzapine to tetrabenazine for the management of Huntington’s chorea
Objective: To compare the efficacy of risperidone and olanzapine to tetrabenazine (TBZ) for the management of Huntington’s chorea in Enroll-HD participants. Background: TBZ is provenly-effective…Submandibular gland is a suitable tissue for alpha synuclein pathology in Parkinson’s disease
Objective: To validate the role of α-synuclein (AS) pathology in submandibular gland (SMG) as a biomarker for Parkinson disease (PD). Background: The pathologic hallmark of…STN-DBS responsive motor complication and pathological gambling in type IV SCA3
Objective: Background: Type IV spinocerebellar ataxia type 3 (SCA3) could present as pure parkinsonism. A bilateral subthalamic nucleus deep brain stimulation (STN-DBS) has been reported…CRISPR/Cas9-based fluorescent tyrosine hydroxylase-reporter lines
Objective: To generate and characterize TH-GFP and -mCherry reporter iPSC lines. Background: Human induced pluripotent stem cells (iPSCs)-based dopaminergic neuronal (iDA) cultures emerged as a…
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