White matter microstructural alterations in Huntington Disease: When neurodegeneration starts?
Objective: The aim of our study is to characterize in detail the white matter (WM) microstructure alterations in Huntington Disease (HD) using the diffusion tensor…Huntington disease like 2 in South Africa
Objective: Background: Since the Huntingtin gene was identified in 1993, it has been recognized that a small proportion of patients with a clinical syndrome resembling…Evolution of Motor and Non-Motor Manifestations in Prodromal Parkinsonism
Objective: To trace the evolution of early motor and non-motor manifestations of synculeinopathy from the stage of idiopathic REM sleep behavior disorder (iRBD) until defined…Clinical profiles of late-onset psychiatric patients with incidental REM sleep without atonia
Objective: The clinical profiles of late-onset psychiatric patients exhibiting incidental REM sleep without atonia (RWA), which is a hallmark of REM sleep behavior disorder (RBD)…Effectiveness and costs of specialised physiotherapy given via ParkinsonNet: A retrospective analysis of medical claims data
Objective: To study the long-term benefits of specialised physiotherapy using the ParkinsonNet approach in real-world practice. Background: Trials show that specialised allied health interventions are…Antiglycine Receptor Antibodies and Rapidly Progressive Corticobasal Syndrome
Objective: To describe the first case of non-paraneoplastic autoimmune encephalitis with antiglycine receptor (anti-GlyR) antibodies manifesting as a Corticobasal Syndrome (CBS) and the response to…The Impact of short in-patient rehabilitation courses for people with Parkinson´s disease
Objective: To find out whether a 10 to 14 days group-based multidisciplinary in-patient rehabilitation course for patients with Parkinson´s disease has any long-term effect on…Clinical features and natural history of pathologically-confirmed corticobasal degeneration: A Japanese validation study of CBD (J-VAC study)
Objective: To elucidate the clinical features and natural history of CBD. Background: Recently, various clinical phenotypes of corticobasal degeneration (CBD) have been reported; on the…Probable MSA presenting initially with urinary retention
Objective: We describe 6 cases of probable MSA presenting with urinary retention/incomplete bladder emptying. Background: MSA is a progressive neurodegenerative adult-onset disease whose clinical features…PROMESA: A randomised, double-blind, placebo-controlled trial to evaluate the progression rate of MSA under EGCG supplementation as anti-aggregation-approach
Objective: To evaluate the safety and tolerability of epigallocatechin gallate (EGCG) in high doses and its efficacy to slow down disease progression in patients with…
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