Investigating the influence of alpha-synuclein promoter (Rep1) polymorphism on cognition, disability and plasma alpha-synuclein levels in Parkinson’s disease
Objective: We sought to investigate the relationship between SNCA Rep1 allele length and cognitive, motor and disability scores in PD, as well with plasma alpha-synuclein…DAT-imaging and clinical phenotypes of Parkinson’s disease
Objective: To evaluate the relationship of motor and nonmotor symptoms with striatal dopaminergic denervation in a cohort of symptomatic PD patients with positive DAT-imaging Background:…Quantitative analysis of DaT uptake and neuromelanin MR contrast in patients with Parkinson’s disease and healthy controls
Objective: To examined quantitative measures of neuromelanin (NM) MRI and DaT-SPECT imaging of the SN and striatum to distinguish PD patients from healthy control subjects…Distinguishing ON from OFF Motor State by Phone Attribute Codes in Patients with Parkinson’s Disease
Objective: To detect differences of speech in patients with PD due to a variant motor state, i.e. ON and OFF. Background: Speech is a highly…Can Preoperative Dopamine Transporter Imaging Predict the Long-Term Outcome of Deep Brain Stimulation in Patients with Parkinson’s Disease?
Objective: The aim of this study is to examine how baseline dopamine transporter imaging, DAT SPECT, is related to the long-term outcome of STN DBS…Cardiac sympathetic denervation can predict the wearing-off phenomenon in patients with Parkinson’s disease
Objective: To investigate whether cardiac sympathetic denervation increases the risk of the early wearing-off phenomenon in Parkinson's disease (PD). Background: Recent studies have suggested that…Potential indicator of antiparkinsonian drug efficacy: an attempt to explore imaging findings
Objective: To clarify the Single photon emission computed tomography (SPECT) findings for evaluating currently unknown antiparkinsonian drug efficacy in Parkinson’s disease (PD) patients. Background: Little…L-Dopa Responsiveness is Correlated to Fluorodeoxyglucose Metabolism and Dopamine Transporter Availability in Parkinson’s Disease
Objective: We aim to explore if the degree of l-dopa responsiveness would be correlated to metabolism level in specific brain areas by using 18F-FDG and…Beta burst coupling across the motor circuit in patients with Parkinson’s disease
Objective: Here, we test the hypothesis that beta bursts not only involve dynamically elevated local synchronisation but also distributed coupling across circuit nodes, further restricting…Circadian modifications in Parkinson disease
Objective: To observe the expression of circadian rhythm related genes Bmal1 and melatonin receptors in different brain regions of 6-OHDA-induced acute Parkinson's disease rats. Background:…
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