Are the MDS-UPDRS-based composite scores clinically applicable?
Objective: Our aim is to evaluate the feasibility of various composite scores based on the Movement Disorder Society-sponsored Unified Parkinson’s Disease Rating Scale (MDS-UPDRS) as…Effects of droxidopa when measuring gait speed, kyphosis, and functional reach in Parkinson’s disease
Objective: To determine if droxidopa improves gait speed, kyphosis, and functional reach in Parkinson’s disease when added to routine care treatment. Background: Fall risk factors…Botulinum toxin in Essential Hand Tremor – A Randomized Double-Blind Placebo-Controlled study with Customized Injection Approach
Objective: To evaluate the safety and efficacy of incobotulinumtoxinA (IncoA) injection for treatment of Essential Tremor (ET). Background: In essential tremor and Parkinson's Disease tremor,…Improvement in Patient Perceived Quality of Life with DaxibotulinumtoxinA for Injection in Adults with Cervical Dystonia
Objective: We describe the quality of life outcome from an open-label trial of daxibotulinumtoxinA for injection (Daxi) in cervical dystonia (CD) as measured by the…Angiotensin-converting enzyme inhibitors are neuroprotective regarding APOE-mediated motor and non-motor experiences for Alzheimer’s dementia but not for dementia with Lewy bodies
Objective: To assess whether angiotensin-converting enzyme (ACE) inhibitors modulate associations of biofluid concentrations and activity of ACE with motor and non-motor experiences in dementia with…Abnormal signaling along the non-canonical molecular cascade GRK6/β-arrestin2/Akt/GSK-3β in the putamen is associated with tardive dyskinesia following chronic haloperidol exposure in a primate model
Objective: To investigate the neurochemical basis of tardive dyskinesia (TD) in an experimental primate model. Background: TD is a potentially irreversible motor complication occurring in…Demographic and Clinical Characteristics of Flunarizine Induced Parkinsonism: Nationwide Data Between 2000 and 2006 in Taiwan
Objective: The calcium channel blockers, such as flunarizine and cinnarizine, and rarely selective serotonin reuptake inhibitors and lithium can produce parkinsonism and tardive syndromes. Background:…An evaluation of the availability and format of information provided to patients who have a new diagnosis of Parkinson’s disease (PD)
Objective: To evaluate if the information provided to a person with Parkinson’s (PwP) is relevant and appropriate for that individual. To also consider the need…Inherited neuromyotonia associated with a dominant-negative KCNQ2 mutation
Objective: To report the phenotypic and genotypic characteristics of a Taiwanese family with inherited neuromyotonia associated with KCNQ2 mutation. Background: Neuromyotonia is a disorder of…Genetic analysis of Wilson’s disease in Taiwan
Objective: Genetic analysis of Taiwanese patients with Wilson’s disease. Background: Wilson’s disease (WD) is an autosomal recessive disorder of copper metabolism. The genetic cause is…
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