Atypical presentation of PANK2 mutation: A case report
Objective: To describe an atypical presentation of a PANK2 mutation. Background: PKAN (Pantothenate-Kinase-Associated Neurodegeneration) is the most common NBIA (Neurodegeneration with brain iron accumulation) disorder,…Comparison of clinical characteristics and treatment outcomes of botulinum neurotoxin in routine clinical practice between hemifacial spasm with and without the Babinski-2 sign in Thai patients: An exploratory study
Objective: To compare the clinical characteristics, along with the treatment outcomes of botulinum neurotoxin (BoNT) between HFS patients with and without the BBK-2 sign as…Identifying therapeutic targets from spontaneous beneficial brain lesions
Objective: To determine whether rare cases in which spontaneously occurring brain lesions improved tremor can be used to identify a therapeutic target. Background: The search…Diencephalic mesencephalic junction abnormalities in adult-onset movement disorders
Objective: To describe two cases of adult-onset movement disorders with diencephalic-mesencephalic junction dysplasia(DMJD). Background: DMJD is a rare malformation characterized by a poorly defined junction…Role of metformin in diabetic aging female rat brain: a future therapy for neurodegenerative diseases
Objective: The objective of this study was to investigate effects of metformin on glucose transporter (GLUT1, GLUT3) expression, intracellular calcium levels, expression of synaptic molecules…Age related changes of cortical effective connectivity during bimanual motor control
Objective: To identify age-related changes of bimanual coordination and characterize the underlying alterations of effective connectivity within the cortical motor system. Background: Exact signal processing…Safinamide add-on therapy increases ON time without dyskinesia in fluctuating Parkinson’s Disease (PD) patients with moderate to severe dyskinesia
Objective: This post-hoc analysis examined safinamide efficacy for providing dyskinesia-free ON time in LID patients. Background: Safinamide has both dopaminergic and glutamate modulating activity. The…Efficacy of opicapone in Parkinson’s disease patients with ‘early’ motor fluctuations: The BIPARK-I double-blind experience
Objective: To evaluate the efficacy of opicapone (OPC) in levodopa-treated Parkinson’s Disease (PD) patients with ‘early’ motor fluctuations. Background: OPC, a novel once-daily COMT inhibitor,…Effect of dual task as rehabilitation therapy in Parkinson’s disease in the UPDRS III
Objective: To determine the effect of the dual task used as Rehabilitation therapy in the UPDRS III of patients with Parkinson's disease. Background: Parkinson's disease…Combined catechol-O-methyl-transferase inhibition and intrajejunal Levodopa infusion: A real-life single-centre experience
Objective: To explore if catechol-O-methyl-transferase inhibition (COMT-I) can prolong the efficacy of daytime intrajejunal Levodopa infusion (IJLI) in Parkinson’s disease (PD) along with a reduction…
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