Computational and Biochemical analysis of lipid raft proteins: A new perspective approach to understand the progression of late onset Parkinson’s disease
Objective: In the current study we report mutations, particularly inPARK-7 gene and their impact on understanding the pathophysiology of Parkinson’s disease (PD); it also lays…Evidence for dysregulation of inflammatory mechanisms involving the NF-κB complex in the living parkinsonian brain
Objective: Sequence RNA in cortical samples taken from living PD patients to detect significant differentially expressed genes (DEGs) and altered biological pathways when compared to…Clinical evaluation of genetic changes of polymerase chain reaction in patients with PD at early stage
Objective: To assess the clinical feature of genetic changes in PARK1 (α-synuclein) and PARK2 with the help of PCR in patients with Parkinson’s disease and…Gender effects on clinical features in LRRK2 G2385R carriers and non-carriers in Parkinson’s disease
Objective: This study was to explore gender effects within the same genetic subtype and role of leucine-rich repeat kinase 2 (LRRK2) G2385R variants within the…Parkinson-related CHCHD2 is necessary for oligomerization of ALS/FTD-related CHCHD10
Objective: Characterization of isogenic CHCHD2, CHCHD10, and CHCHD2/10 double knockout out cell lines with assays of mitochondrial function, mitochondrial sublocalization, and homo- and heterodimerization. Background:…Cerebellar atrophy in different motor and non-motor subtypes of Parkinson’s disease
Objective: The cerebellum is involved in Parkinson’s disease (PD). This study was to investigate, using MRI and voxel-based morphometry (VBM), morphometric changes of cerebellum in…Ultrasonographic signatures associated with movement disorders (USA-MD study): A population-based longitudinal study
Objective: To identify sonographic biomarkers of PD (Parkinson´s disease). Background: Study of Parkinson’s disease biomarkers could lead us to identify the disease at its earlier…Research on nearinfrared brain function imaging for Freezing of Gait in Parkinson’s Disease
Objective: In the study ,fNIRS technique was used to study the activation level and activation mode of prefrontal cerebral cortex for patients with FOG under…Microstructural changes in white and grey matter related to apathy, depression and anxiety in de novo Parkinson’s disease patients
Objective: To study microstructural changes in grey and white matter in early drug-naïve Parkinson's disease (PD) patients and correlate these changes with neuropsychological manifestations. Background:…Functional connectivity changes in relation to dopaminergic decline in Parkinson’s over time: A resting-state fMRI and 11C-PE2I PET imaging study
Objective: To evaluate the functional connectivity patterns of basal ganglia subdivisions in relation to dopamine transporter density and motor features in patients with PD at…
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