The effect of thalamic and subthalamic deep brain stimulation on speech in patients with essential tremor: A prospective, randomized, double-blind crossover study
Objective: To investigate the effect of thalamic (ventral intermediate nucleus, VIM) and subthalamic (posterior subthalamic area, PSA) deep brain stimulation (DBS) in patients with essential…Somatosensory temporal discrimination in Parkinson’s disease, dystonia and essential tremor: Pathophysiological and clinical implications
Objective: To investigate whether changes in the somatosensory temporal discrimination threshold (STDT) in Parkinson’s disease (PD) and dystonia reflect the involvement of specific neural structures…Neuropsychological Assessment of Cognitive Dysfunction in Parkinson’s Disease: A Comparison of Four Screening Instruments
Objective: To compare four different neuropsychological screening instruments (DemTect, Mattis Dementia Rating Scale (MDRS), Mini Mental State Examination (MMSE) and Parkinson Neuropsychometric Dementia Assessment (PANDA))…Affective Theory of Mind Impaired in Parkinson’s Disease: Negative- and Neutral- specific impairments of Emotion State Decoding
Objective: The primary aim of this study was to investigate whether the ability to interpret positive, negative, or neutral emotion from a pair of photographed…Hypertriglyceridemia is associated with Parkinson disease mild cognitive impairment (PD-MCI)
Objective: Our study aimed to characterise Parkinson disease (PD) mild cognitive impairment (PD-MCI) in early PD and to identify biomarkers associated with PD-MCI. Background: Approximately…Turning during gait is associated with gray matter density of the nucleus basalis of Meynert in Parkinson’s disease
Objective: To examine whether turning during gait is associated with gray matter (GM) density of the nucleus basalis of Meynert (nbM) and attention in people…Early synaptic loss and synaptic instability in a mouse model of prodromal Parkinson’s disease
Objective: In order to elucidate very early pathologis of Parkinson’s disease (PD), we focused on synaptic pathologies in a newly developed mouse model of prodromal…Knockdown of eEF1A2 reduced neuronal survival in a SH-SY5Y cellular model of Parkinson’s disease through the PI3K/Akt/mTOR pathway
Objective: To investigate whether eEF1A2 promotes neuronal survival through PI3K/Akt/mTOR pathway in a toxin-induced Parkinson’s disease model. Background: Parkinson’s disease is a common neurodegenerative disorder…Ubiquitin carboxyl-terminal hydrolase 1 (UCHL1) -mediated ubiquitination attributed to localization of Mortalin to mitochondria
Objective: The pathogenic mechanism of UCHL1 in PD remains unclear. In this study, we aimed to investigate the role of UCHL1 in the pathogenesis of…Relationship between cyclooxygenase-2 gene polymorphisms and Parkinson’s disease susceptibility in Chinese Han population
Objective: To investigate relationship between the cyclooxygenase-2 (COX-2) gene promoter region (rs20417, rs689466, rs689465) and 3'untranslated region (rs5275) polymorphisms with Parkinson’s disease (PD) susceptibility in…
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