Speech in Huntington’s Disease
Objective: To review existing literature on speech function in Huntington’s disease (HD) across the disease spectrum. Background: Impairment in speech production affects the majority of…Assessing the potential of EEG as a biomarker in Huntington’s disease using machine learning automatic classification
Objective: To construct an automatic classifier distinguishing healthy controls from Huntington’s disease (HD) gene carriers using quantitative electroencephalography (qEEG) and to derive qEEG features that…Predicting Alpha-Synuclein Pathology by REM Sleep Behavior Disorder Diagnosis
Objective: Determine sensitivity, specificity and predictive value of clinician diagnosed probable REM sleep behavior disorder (PRBD) in predicting alpha-synuclein pathology. Background: Inability to accurately diagnose…Parkinsonism with rare sequence variants in VPS35 and FBXO7 genes associated with Lewy body pathology
Objective: To detect a neuropathological background of parkinsonism associated with rare sequence variants in the VPS35 and FBXO7 genes. Background: A total of 23 gene…Adolescent onset RBD converting to PD after 48 years
Objective: To present a patient with adolescent onset dream enactment behaviour who developed PD 48 years later. Background: RBD typically occurs after age 50, and…Parkinson’s disease-related non-motor features as risk factors for post-operative delirium in spinal surgery
Objective: We investigated the association between PD-related NMSs and postoperative delirium in old people undergoing elective spinal surgery. Background: The clinical features of postoperative delirium…C-spine injury with progressive gait difficulty, drop foot, bizarre gait and serum positive stiff person syndrome: A case report
Objective: A complicated case presented with trauma history and insidious onset of stiff person syndrome. Background: Stiff person syndrome is a rare neurological disorder characterized…Reversible Extrapyramidal features as unusual presentation of central pontine myelinolysis: A case report
Objective: To be acquainted with the extrapyramidal symptoms developed during the course of central pontine myelinolysis. To emphasize the importance of neuroimaging in the diagnosis…A case of levodopa responsive rapid onset dystonia-parkinsonism
Objective: We describe and demonstrate by video a young man with rapid onset dystonia parkinsonism who has a robust response to levodopa. Background: Rapid onset…Methylphenidate in Progressive Supranuclear Palsy [PSP] – Old drug, New Indications?
Objective: To evaluate whether Methylphenidate can improve some symptoms of PSP. Background: PSP is a neurodegenerative disorder with limited therapeutic options. Methylphenidate[MPH] , a drug…
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