MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2018 International Congress

    Disease Modeling of DYT1 Using Patient Induced Pluripotent Stem Cells

    A. Dinasarapu, D. Sutcliffe, M. Zwick, H. Jinnah (Atlanta, GA, USA)

    Objective: To create a resource of induced pluripotent stem cells (iPSCs) as models for exploring mechanisms of pathogenesis in DYT1 dystonia. Background: DYT1 an autosomal…
  • 2018 International Congress

    How much does botulinum toxin injection interval impact upon patient satisfaction in the routine treatment of cervical dystonia?

    T. Chung, D. Charles, C. Colosimo, V. Misra, P. Maisonobe, S. Om (São Paulo, Brazil)

    Objective: Evaluate the impact of injection interval on satisfaction with botulinum toxin-A (BoNT-A) treatment in cervical dystonia (CD) patients who have been treated for 1…
  • 2018 International Congress

    “Stiff Young Woman”: Case report

    M. Sousa, R. Varela, D. Carneiro, C. Januário, A. Morgadinho (Coimbra, Portugal)

    Objective: To describe a rare presentation of a young-onset Stiff Person Syndrome patient. Background: The Stiff-Person syndrome (SPS) is classically characterized by progressive stiffness with…
  • 2018 International Congress

    Gamma Knife Radiosurgery for Generalised Dystonia: Is It The Last Part in The Ship of Theseus

    M. Tripathi (Chandigarh, India)

    Objective: To evaluate the role of radiosurgical thalamotomy in cases of medically refractory generalised dystonia in current era. Background: Gamma knife radiosurgery has been proved…
  • 2018 International Congress

    Long-term Outcomes with Rescue Target Deep Brain Stimulation in Patients with Dystonia

    A. Hatcher, A W. Shukla, P. Zeilman, E. Ofori, D. Vaillancourt, K. Foote, M. Okun (Gainesville, FL, USA)

    Objective: Determine the long-term outcomes of rescue target deep brain stimulation (DBS) surgery in dystonia. Background: Globus pallidus internus (GPi) and subthalamic nucleus (STN) are…
  • 2018 International Congress

    Prodromal features of Parkinson’s disease in women

    K. Hughes, X. Gao, J. Baker, C. Stephen, I. Kim, L. Valeri, M. Schwarzschild, A. Ascherio (Boston, MA, USA)

    Objective: To identify how prodromal features interact to determine Parkinson’s disease (PD) risk in women. Background: The neuronal loss that leads to PD progresses insidiously…
  • 2018 International Congress

    Tendency towards being a “Morning person” increases risk of Parkinson’s disease: evidence from Mendelian randomisation

    A. Noyce, D. Kia, K. Heilbron, J. Jepson, G. Hemani, D. Hinds, D. Lawlor, G. Davey Smith, J. Hardy, A. Singleton, M. Nalls, N. Wood (London, United Kingdom)

    Objective: To explore the causal relationship between circadian rhythm and Parkinson's disease (PD), and coffee consumption and PD, using Mendelian randomisation (MR). Background: Circadian rhythm…
  • 2018 International Congress

    Parallel evaluation of mutant huntingtin and neurofilament light in Huntington’s disease

    L. Byrne, F. Rodrigues, E. Johnson, E. De Vita, C. Czech, S. Schobel, R. Scahill, A. Heslegrave, H. Zetterberg, W. Wild (London, United Kingdom)

    Objective: To assess cerebrospinal fluid (CSF) mutant Huntingtin (mHTT), and CSF and plasma neurofilament light (NfL) in Huntington’s disease (HD). Background: HD is a progressive…
  • 2018 International Congress

    Exploration of insight competence in Huntington’s disease supplemental to a cognitive debriefing study for the FuRST2.0 rating scale

    R. Fuller, P. Feigenbaum, C. Fitzer-Attas, N. La Pelle, S. Luo, C. Sampaio, G. Stebbins (Princeton, NJ, USA)

    Objective: Evaluate insight of functional impairment in premanifest and early-manifest Huntington’s disease (HD). Background: Following the guidelines of the US Food and Drug Administration Clinical…
  • 2018 International Congress

    Changes in brain network activation (BNA) in patients with fragile x-associated tremor/ataxia syndrome (FXTAS)

    T. Fay Karmon, S. Israeli-Korn, G. Yahalom, G. Issachar, Y. Yahav, A. Geva, Z. Peremen, S. Hassin-Baer (Ramat Gan, Israel)

    Objective: We aimed to assess the ability of Brain Network Activation (BNA) EEG analysis to differentiate between patients with fragile X-associated tremor/ataxia syndrome (FXTAS), Parkinson’s…
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