PPMI driven sample size estimation for clinical trials in Parkinson’s disease
Objective: To utilize clinical, imaging and CSF data from the Parkinson’s Progression Markers Initiative (PPMI) to estimate the sample size for disease modification studies in…Angiotensin-converting enzyme inhibitors are neuroprotective regarding APOE-mediated motor and non-motor experiences for Alzheimer’s dementia but not for dementia with Lewy bodies
Objective: To assess whether angiotensin-converting enzyme (ACE) inhibitors modulate associations of biofluid concentrations and activity of ACE with motor and non-motor experiences in dementia with…Abnormal signaling along the non-canonical molecular cascade GRK6/β-arrestin2/Akt/GSK-3β in the putamen is associated with tardive dyskinesia following chronic haloperidol exposure in a primate model
Objective: To investigate the neurochemical basis of tardive dyskinesia (TD) in an experimental primate model. Background: TD is a potentially irreversible motor complication occurring in…Demographic and Clinical Characteristics of Flunarizine Induced Parkinsonism: Nationwide Data Between 2000 and 2006 in Taiwan
Objective: The calcium channel blockers, such as flunarizine and cinnarizine, and rarely selective serotonin reuptake inhibitors and lithium can produce parkinsonism and tardive syndromes. Background:…An evaluation of the availability and format of information provided to patients who have a new diagnosis of Parkinson’s disease (PD)
Objective: To evaluate if the information provided to a person with Parkinson’s (PwP) is relevant and appropriate for that individual. To also consider the need…Inherited neuromyotonia associated with a dominant-negative KCNQ2 mutation
Objective: To report the phenotypic and genotypic characteristics of a Taiwanese family with inherited neuromyotonia associated with KCNQ2 mutation. Background: Neuromyotonia is a disorder of…Genetic analysis of Wilson’s disease in Taiwan
Objective: Genetic analysis of Taiwanese patients with Wilson’s disease. Background: Wilson’s disease (WD) is an autosomal recessive disorder of copper metabolism. The genetic cause is…Reversible asymmetric parkinsonism and vertical gaze limitation as an initial manifestation of dural arteriovenous fistula
Objective: Our aim is to report a case of unusual manifestation of dural arteriovenous fistula (DAVF) which showed reversible asymmetric parkinsonism and vertical gaze limitation…Comparison of Volumetric MRI measurements between Dementia with Lewy bodies and prodromal Lewy body disease
Objective: To compare the volumetric changes between patients at prodromal stage of Lewy body disese and individuals with dementia with Lewy Bodies. Background: Volumetric magnetic…Neuromodulatory propensity of Ginko biloba to offset rotenone induced behaviour and biochemical alteration
Objective: The aim of present study was to evaluate neuromodulatory propensity of Gingko Biloba in rotenone induced Mice Model of Parkinson Disease in terms of…
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