Somatosensory temporal discrimination in Parkinson’s disease, dystonia and essential tremor: Pathophysiological and clinical implications
Objective: To investigate whether changes in the somatosensory temporal discrimination threshold (STDT) in Parkinson’s disease (PD) and dystonia reflect the involvement of specific neural structures…Neuropsychological Assessment of Cognitive Dysfunction in Parkinson’s Disease: A Comparison of Four Screening Instruments
Objective: To compare four different neuropsychological screening instruments (DemTect, Mattis Dementia Rating Scale (MDRS), Mini Mental State Examination (MMSE) and Parkinson Neuropsychometric Dementia Assessment (PANDA))…Affective Theory of Mind Impaired in Parkinson’s Disease: Negative- and Neutral- specific impairments of Emotion State Decoding
Objective: The primary aim of this study was to investigate whether the ability to interpret positive, negative, or neutral emotion from a pair of photographed…Hypertriglyceridemia is associated with Parkinson disease mild cognitive impairment (PD-MCI)
Objective: Our study aimed to characterise Parkinson disease (PD) mild cognitive impairment (PD-MCI) in early PD and to identify biomarkers associated with PD-MCI. Background: Approximately…Dual task walking differentially affects toe clearance in Lewy body disease: A contributor to dynamic falls risk?
Objective: To evaluate the change in gait and minimum toe clearance when walking under dual task in different dementia sub-types as a contributor to dynamic…Early synaptic loss and synaptic instability in a mouse model of prodromal Parkinson’s disease
Objective: In order to elucidate very early pathologis of Parkinson’s disease (PD), we focused on synaptic pathologies in a newly developed mouse model of prodromal…Knockdown of eEF1A2 reduced neuronal survival in a SH-SY5Y cellular model of Parkinson’s disease through the PI3K/Akt/mTOR pathway
Objective: To investigate whether eEF1A2 promotes neuronal survival through PI3K/Akt/mTOR pathway in a toxin-induced Parkinson’s disease model. Background: Parkinson’s disease is a common neurodegenerative disorder…Ubiquitin carboxyl-terminal hydrolase 1 (UCHL1) -mediated ubiquitination attributed to localization of Mortalin to mitochondria
Objective: The pathogenic mechanism of UCHL1 in PD remains unclear. In this study, we aimed to investigate the role of UCHL1 in the pathogenesis of…Relationship between cyclooxygenase-2 gene polymorphisms and Parkinson’s disease susceptibility in Chinese Han population
Objective: To investigate relationship between the cyclooxygenase-2 (COX-2) gene promoter region (rs20417, rs689466, rs689465) and 3'untranslated region (rs5275) polymorphisms with Parkinson’s disease (PD) susceptibility in…Frequency of the LRRK2 and GBA mutations in Russian population with Parkinson’s disease
Objective: To estimate the frequency of LRRK2 mutation (G2019S) and GBA mutations (N370S, L444P) and polymorphic variants (E326K, T369M) in PD and controls in the…
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