Effect of bedtime levodopa/carpidopa/entacapone (Stalevo®) on sleep disturbance in patients with Parkinson’s disease with motor fluctuation
Objective: To investigate the efficacy of levodopa/carbidopa/entacapone (Stalevo®) at bedtime on sleep disturbance in patients with Parkinson’s disease (PD) who have motor fluctuation. Background: Sleep…The Effect of Sleep Deprivation on Short-Term Memory and Emotion of Rotenone Treated Zebrafish Model of Parkinson Disease
Objective: We investigated the long-term consequences of sleep deprivation on short-term memory and emotion using a rotenone treated zebrafish model of Parkinson disease. Background: Parkinson…Non-motor outcomes of subthalamic DBS in PD depend on the location of volume of activated tissue
Objective: To investigate the impact of stimulation location on non-motor symptoms (NMS) in PD patients with DBS in the subthalamic nucleus (STN) via an analysis…Is repetitive transcranial magnetic stimulation an effective tool to treat pain in Parkinson’s Disease?
Objective: An open label pilot study designed to assess safety and efficacy of repetitive transcranial magnetic stimulation(rTMS) to treat pain in Parkinson’s Disease. Background: Pain…Commonalities of prodromal non-motor symptoms between movement disorders
Objective: This study reviewed and compared evidence of nonmotor symptoms in prodromal phases in movement disorders including Parkinson disease, Atypical Parkinsonism (MSA, DLB, PSP), Huntington…Interaction of amyloidogenic proteins in pancreatic β cells from subjects with synuclenopathies
Objective: We have investigated whether deposits of phosphorylated α-synuclein might be present in pancreatic tissue of subjects with synucleinopathies. Background: Parkinson’s disease patients experience a…Effect of Urinary Dysfunction on Fatigue Syndrome in Parkinson’s disease
Objective: to investigate the relationship between urinary dysfunction and fatigue syndrome in Parkinson`s disease Background: Fatigue syndrome (FS) is an overwhelming sense of tiredness, lack…Validation of protein phosphatases that regulate the LRRK2 phosphorylation cycle
Objective: To identify and validate candidate phosphatases regulating the LRRK2 phosphorylation cycle. Background: Mutations in the gene encoding leucine-rich repeat kinase 2 (LRRK2) are one…Role of microglia in the transmission of α-syn-containing exosomes
Objective: we investigated the role of microglia in the transmission of α-syn-containing exosomes and offer a new insight into the mechanism of PD pathogenesis. Background:…Neurophysiological correlates of bradykinesia in Parkinson’s disease
Objective: In the present study we aimed to investigate whether objective measures of bradykinesia in Parkinson’s disease have any relationship with neurophysiological measures in primary…
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