Gamma Knife Radiosurgery for Generalised Dystonia: Is It The Last Part in The Ship of Theseus
Objective: To evaluate the role of radiosurgical thalamotomy in cases of medically refractory generalised dystonia in current era. Background: Gamma knife radiosurgery has been proved…Long-term Outcomes with Rescue Target Deep Brain Stimulation in Patients with Dystonia
Objective: Determine the long-term outcomes of rescue target deep brain stimulation (DBS) surgery in dystonia. Background: Globus pallidus internus (GPi) and subthalamic nucleus (STN) are…West Sweden Parkinson Objective Measurement Registry Study (WestPORTS)
Objective: To study a population representative Parkinson’s Disease (PD) patient cohort characterized with objective 6x24h home measurements using the Parkinson Kinetigraph (PKG, Global Kinetics). To…Levodopa-induced dyskinesias in Parkinson disease: A population-based cohort study in Olmsted County, MN (1991-2010)
Objective: To assess the frequency of dyskinesias in a population based-cohort of Parkinson’s disease patients. Background: Levodopa-induced dyskinesias are complications that may impact quality of…Speech in Huntington’s Disease
Objective: To review existing literature on speech function in Huntington’s disease (HD) across the disease spectrum. Background: Impairment in speech production affects the majority of…Assessing the potential of EEG as a biomarker in Huntington’s disease using machine learning automatic classification
Objective: To construct an automatic classifier distinguishing healthy controls from Huntington’s disease (HD) gene carriers using quantitative electroencephalography (qEEG) and to derive qEEG features that…Predicting Alpha-Synuclein Pathology by REM Sleep Behavior Disorder Diagnosis
Objective: Determine sensitivity, specificity and predictive value of clinician diagnosed probable REM sleep behavior disorder (PRBD) in predicting alpha-synuclein pathology. Background: Inability to accurately diagnose…Parkinsonism with rare sequence variants in VPS35 and FBXO7 genes associated with Lewy body pathology
Objective: To detect a neuropathological background of parkinsonism associated with rare sequence variants in the VPS35 and FBXO7 genes. Background: A total of 23 gene…Adolescent onset RBD converting to PD after 48 years
Objective: To present a patient with adolescent onset dream enactment behaviour who developed PD 48 years later. Background: RBD typically occurs after age 50, and…Rotenone model of Parkinson’s disease: The dosing options in mice revisited
Objective: In the present study we have used various dosing protocols to induce the PD-like symptoms with the administration of rotenone in mice. Background: Parkinson's…
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