Alteration of the fecal microbiota in Chinese patients with Parkinson’s disease
Objective: Emerging evidences suggest that gut microbiota dysbiosis plays a role in Parkinson’s disease (PD). However, the alterations in fecal microbiome in Chinese PD patients…Molecular Genetics and Functional Studies of LRRK2 Gene Variations in Parkinson’s Disease
Objective: To evaluate the function role of ROC domain in the brains of LRRK2 transgenic mice model and normal control mice. Background: Mutations in leucine-rich…The Association between Infections and Parkinson Disease: A Systematic Review and Meta-analysis
Objective: Our study aimed to recapitulate and summarize the findings from the literature to provide an overview on the correlation between infection and PD. Background:…Deletion of GBA2 in neuronopathic Gaucher’s disease medaka can’t rescue the phenotype
Objective: This study was performed to determine the pathological role of GBA2 in the CNS in GD and GBA1-related PD. Background: Parkinson’s disease (PD) is…Protective effects of Mucuna pruriens seed on rat brain: A therapeutic potential drug for Parkinson’s disease
Objective: Objective of present study was evaluate neuroprotective and antiparkinson effects of Mp seed extract on Parkinsons brain of rats. Background: Parkinson’s disease (PD) is…Clinical correlates of stuttering in advanced Parkinson’s disease
Objective: We investigated clinical characteristics of a large number of advanced Parkinson’s disease (PD) patients to reveal risk factors for the development of stuttering and…Modulation of CaMKIIa-NR2B interaction in levodopa-induced dyskinesia in 6-OHDA- lesioned Parkinson’s rats
Objective: In the present study, therefore, we examined the relationship between CaMKII and NR2B in levodopa-induced dyskinesia rats. Background: Long-term treatment with L-dopa leads to…Impaired performance on measures of goal-directed behavior are associated with greater caregiver burden in Parkinson’s disease
Objective: To assess the utility of the Philadelphia Apathy Computerized Task (PACT) in measuring goal-directed behavior in Parkinson’s disease (PD). Background: Impairment in goal-directed behavior…Patient Experience of Parkinson’s Disease Psychosis Management
Objective: To understand the experience and management of Parkinson’s disease psychosis (PDP). Background: PDP is a troubling non-motor symptom of Parkinson’s disease. Clinical approaches to…Rasch analysis of the Hospital Anxiety and Depression Scale among patients with early-stage Parkinson’s disease
Objective: We aim to assess the psychometric properties of the Korean version of Hospital Anxiety and Depression Scale (HADS) in a sample of early-stage Parkinson's…
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