Unraveling gut microbiota in Parkinson’s disease and atypical parkinsonism
Objective: (1) To evaluate the differences in gut microbiota among Parkinson’s disease (PD), atypical parkinsonism (i.e. multiple system atrophy [MSA] and progressive supranuclear palsy [PSP])…Enhancing protein palmitoylation is protective in alpha-synuclein dependent cytotoxicity
Objective: To determine if enhancement of protein palmitoylation benefits alpha-synuclein (aS) dependent vesicular trafficking defects and cytotoxicity. Background: Recent studies suggest that vesicular trafficking defects…Cortical correlates of dual-task turning with and without freezing of gait
Objective: This study investigated the relationship between prefrontal cortex (PFC) activity and turning characteristics with and without a dual-task in in people with Parkinson’s disease…Erotophonophilia and severe impulse control disorder in a patient with Parkinson’s disease
Objective: N/A Background: Paraphilia a form of hyper sexuality is a rare complication of dopaminergic drugs used in the treatment of Parkinson's disease (PD). We…Depression and associated factors in nondemented Chinese patients with Parkinson’s disease
Objective: This study aimed to estimate the prevalence and identify potential risk factors influencing depression in 519 consecutive nondemented Chinese PD patients. Background: Depression is…Assessing the Quality of Economic Evaluation of Treatment Options for Parkinson’s disease Using the Quality of Health Economic Studies (QHES) Scale
Objective: The objective of this study was to critically appraise all the published evidences on the economic evaluation of treatment options for Parkinson’s disease. Background:…Are the MDS-UPDRS-based composite scores clinically applicable?
Objective: Our aim is to evaluate the feasibility of various composite scores based on the Movement Disorder Society-sponsored Unified Parkinson’s Disease Rating Scale (MDS-UPDRS) as…Ankle proprioception and postural instability in Parkinson’s disease
Objective: To determine: 1. Is there a correlation between central and peripheral proprioception in Parkinson’s disease? 2. Does postural instability increase with lack of vision…Linking neuroplastic effects to behavioral changes after balance training in Parkinson’s disease: a study protocol of a randomized controlled trial
Objective: In this randomized controlled trial, we will determine the effects of a highly challenging balance training (the HiBalance program) on balance, gait, cognition and…PPMI driven sample size estimation for clinical trials in Parkinson’s disease
Objective: To utilize clinical, imaging and CSF data from the Parkinson’s Progression Markers Initiative (PPMI) to estimate the sample size for disease modification studies in…
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