Mov Disord Vol 33, Suppl 2 Archives - Page 42 of 177 - MDS Abstracts

2018 International Congress
Multi-limb dual-task cost in Parkinson disease: Evaluating effects of implicit and explicit cues
T. McIsaac, R. Cohen, R. Bay, J. Gupta, C. Adler (Mesa, AZ, USA)
Objective: To evaluate the effects of explicit and implicit task prioritization on reaching and foot-pedal tracking in people with Parkinson disease (PD). Background: PD affects…
2018 International Congress
α-Synuclein induced dopaminergic neurons mitochondrial dysfunction via cytochrome c oxidase subunit 2
D. Lin (Guangzhou, China)
Objective: To investigate the mechanism of how α-Syn injure the the dopaminergic neurons. Background: The misfolded α-Synuclein(α-Syn) transferring from cells to cells as prion protein…
2018 International Congress
Association of GALC, ZNF184 and rs2280104 with PD in southern Chinese
G. Li, J. Liu, S.S. Cui, J.J. Du, P.C. Zhang, J.F. Ma, S.D. Chen (Shanghai, China)
Objective: The aim of the study was to investigate the relationship between 12 single nucleotide polymorphisms (SNPs) and Parkinson’s disease (PD) in Chinese population. Background:…
2018 International Congress
Identification of gut microbial genes in Parkinson’s disease by shotgun metagenomic analysis
Y. Qian, X. Yang, S. Xu, S. Chen, Q. Xiao (Shanghai, China)
Objective: To carry out deep analysis on gut microbiome in patients with Parkinson’s disease (PD) and to evaluate the potential application for diagnosing PD patients…
2018 International Congress
Lysosphingolipids accumulation in macrophage model of Gaucher disease
M. Nikolaev, A. Kopytova, K. Senkevich, A. Emelyanov, G. Baydakova, E. Zakharova, G. Salogub, S. Pchelina (Gatchina, Russian Federation)
Objective: The aim of this study was to investigate if GCase deficiency in macrophage model of GD lead to lysosphingolipids accumulation. Background: Mutations in the…
2018 International Congress
The Parkinson’s Families Project: A family-based study of early onset and familial Parkinson’s disease
M. Tan, A. Costantini, S. Lubbe, E. Brown, J. Bras, N. Wood, A. Schapira, J. Hardy, H. Morris (London, United Kingdom)
Objective: The aim of this study is to identify new genetic variants that cause or predispose to Parkinson’s disease (PD). Our secondary aim is to…
2018 International Congress
Further insights into excitatory-inhibitory balance of the primary motor cortex in Parkinson’s disease: A triple-pulse stimulation study
Y. Shirota, Y. Terao, Y. Ugawa, R. Hanajima (Tokyo, Japan)
Objective: To characterize intracortical facilitation and inhibition of the primary motor cortex (M1) in Parkinson’s disease (PD) using transcranial magnetic stimulation (TMS). Background: Since introduction…
2018 International Congress
Olfactory dysfunction, sleep disturbances, neuronal loss, and regional brain atrophy in an inducible mouse model of Alpha-Synucleinopathy
E. Brison, S. Zehntner, A. Zijdenbos, K. Luk, B. Bedell (Montreal, QC, Canada)
Objective: The objective of this work is to develop a unique mouse model of spreading α-synucleinopathy to accelerate the development of novel disease-modifying treatments for…
2018 International Congress
Substantia nigra T1 maps for the diagnosis of Parkinson’s disease
C. Juri, L. Tapia, J. Cruz, S. Uribe, M. Andia (Santiago, Chile)
Objective: To evaluate if the T1 value (measured in ms) in the substantia nigra (SN) is reduced in Parkinson disease (PD) patients as compared with…
2018 International Congress
Hypometabolism of the posterior parietal cortex in Parkinson’s disease with mild cognitive impairment predicts the conversion to dementia: 5-year longitudinal observations
KW. Park, NR. Choi, JH. Ko, SJ. Kim, SJ. Chung, CS. Lee (Seoul, Republic of Korea)
Objective: To investigate the neuroimaging marker that predict the conversion of mild cognitive impairment (MCI) to dementia in Parkinson’s disease (PD) patients. Background: Patients with…