Bidirectional gut-to-brain and brain-to-gut propagation of α-synuclein pathology in non-human primates
Objective: The prototypic synucleinopathy Parkinson's disease (PD) is hypothesized to spread out from the enteric nervous system (i.e. the gut) via the vagal nerve up…Unveiling the function of altered gut microbiota composition in Parkinson’s disease
Objective: To investigate the gut microbiome and metabolome in Parkinson’s disease (PD). Background: Recent evidence revealed that gut microbes promote alpha-synuclein pathology and motor deficits…Salivary Alpha-Synuclein a new tool for the diagnosis of Parkinson’s disease?
Objective: The aim of the PARKSYN study was to test the utility of salivary alpha-synuclein (a-syn) concentration in the differential diagnosis between Parkinson's disease (PD)…Serum Leptin levels in Iranian patients with Parkinson’s disease
Objective: Parkinson’s disease (PD) is the second most common neurodegenerative disorder that frequently affects elderly population worldwide. Initially, PD was known as a motor disorder…Effects of Glial Heme Oxygenase-1 on Neuronal Alpha-Synuclein in the GFAP.HMOX1 Mouse Model of Parkinson’s Disease
Objective: To determine whether astroglial HO-1 transduces environmental and endogenous stressors into patterns of neural damage which promote the toxicity of neuronal alpha-synuclein. Background: The…Classification of Dopaminergic-State and Motor Activity by Theta, Beta and Gamma Activity in Parkinson’s Disease
Objective: To test whether machine learning algorithms are suitable to classify dopamine and behavioral states in Parkinson’s patients (PD). Background: While motor symptoms of PD…Evaluation of affective temperament and bipolarity among patients with Parkinson’ s disease
Objective: To compare the bipolarity and affective temperament scores between patients with Parkinson’s Disease (PD) and healthy controls. Background: Mood disorders are the most common…Evaluation of impulsivity in Parkinson’ s disease
Objective: To evaluate the impulsivity in patients with Parkinson’s Disease. Background: Parkinson’s disease (PD) is a chronic, neurodegenerative, progressive disease characterized with cardinal motor symptoms…Depression, apathy, fatigue in Parkinson with or without STN DBS
Objective: To determine the prevalence of depression, evaluate the relationship between depression, apathy and fatigue, and the impact of STN DBS on the same symptoms.…Prevalence of Patient-Reported Symptoms of Dysphonia and Dysphagia in Movement Disorder Patients at an Academic Medical Center
Objective: To determine the prevalence of patient-reported quality of life (QOL) measures of dysphonia and dysphagia in movement disorder patients at an academic medical center.…
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