Evaluation of pain in Parkinson’s disease
Objective: To determine the prevalence of pain, types and characteristics of pain and the effect of pain on depression and daily living activities in early…Proteomic analysis of tear-fluid reveals disease-specific patterns in patients with Parkinson’s Disease
Objective: In this study, we set out to analyse changes of tear fluid (TF) proteome in Parkinson's Disease (PD) patients compared to age-matched controls (AMC)…Clinical differences between Parkinson’s disease motor phenotypes. Results from the COPPADIS Study Cohort
Objective: To describe the prevalence of different motor phenotypes in a large cohort of Parkinson´s disease (PD) patients and to analyze their clinical features in…Preliminary Study of Depression in Parkinson’s Disease with Diffusion Tensor Imaging
Objective: To explore the relationship between cognitive impairment in Parkinson’s Disease(PD) and the microstructure changes of brain region of interest(ROI) in diffusion tensor imaging(DTI). Background:…Impact of injection guidance techniques on the efficacy and safety of incobotulinumtoxinA for sialorrhea
Objective: SIAXI (NCT02091739), a pivotal double-blind, randomised, placebo-controlled study with an extension period (EP), assessed the efficacy and safety of incobotulinumtoxinA 75 or 100 U…Validation of a patient/caregiver questionnaire to evaluate nocturnal hypokinesia in Parkinson’s disease
Objective: To develop and validate a novel questionnaire to assess various aspects related to problems experienced by PD patients when turning in or getting out…Bidirectional gut-to-brain and brain-to-gut propagation of α-synuclein pathology in non-human primates
Objective: The prototypic synucleinopathy Parkinson's disease (PD) is hypothesized to spread out from the enteric nervous system (i.e. the gut) via the vagal nerve up…Unveiling the function of altered gut microbiota composition in Parkinson’s disease
Objective: To investigate the gut microbiome and metabolome in Parkinson’s disease (PD). Background: Recent evidence revealed that gut microbes promote alpha-synuclein pathology and motor deficits…Salivary Alpha-Synuclein a new tool for the diagnosis of Parkinson’s disease?
Objective: The aim of the PARKSYN study was to test the utility of salivary alpha-synuclein (a-syn) concentration in the differential diagnosis between Parkinson's disease (PD)…Serum Leptin levels in Iranian patients with Parkinson’s disease
Objective: Parkinson’s disease (PD) is the second most common neurodegenerative disorder that frequently affects elderly population worldwide. Initially, PD was known as a motor disorder…
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