Microglial activation, white matter and hippocampal damage correlate with cognitive impairment in chronic cerebral hypoperfused and MPTP-lesioned mice
Objective: We hypothesize that cerebral hypoperfusion may influence the cognitive function of PD animal models. To investigate the effects of cerebral hypoperfusion and microangiopathy on…Correlation between mood and behavioral disorders and quality of life in patients with Parkinson’s disease
Objective: The aim of this study was to investigate if the mood and behavioral disorders could be correlate with quality of life in patients with…Parkinson’s disease anxiety is associated with Lewy bodies in the Anterior Cingulate
Objective: The goal of this study is to determine if there is an association between anxiety and the presence and regional distribution of Lewy bodies…Dissociate effect of dopaminergic therapy in reward expectation and prediction error in PD patients with comorbid impulse control disorder
Objective: To study EEG oscillatory activity associated to reward prediction error in Parkinson’s disease (PD) patients with impulse control disorders (ICD) and determine how dopaminergic…FuRST2.0: Development of a modified functional rating scale for use in premanifest and early-manifest Huntington’s disease
Objective: Develop a patient-reported outcome (PRO) modification of the Functional Rating Scale for pre-Huntington Disease (FuRST-pHD) using focus group, Delphi panel and cognitive pre-testing methodology.…