Natural history of RBD in Parkinson´s disease and response to dopaminergic and non-dopaminergic antiparkinsonian treatment
Objective: To assess the natural history of rapid eye movement sleep behavior disorder (RBD) in patients with Parkinson´s disease (PD) and clarify its response to…Impact of Late-onset REM Sleep Behavior Disorder on the Symptoms of Parkinson’s Disease
Objective: To investigate whether PSG-proven late-onset RBD is associated with the PD symptoms in the Japanese population. Background: Rapid eye movement sleep behavior disorder (RBD)…Non-motor symptoms of Parkinson’s disease: Evaluation of urinary disorders
Objective: Violation of urination, as a manifestation of autonomic failure is common to many patients with Parkinson's disease (PD) and is a very actual. Background:…Non motor symptoms in parkinsonism: A cross sectional study
Objective: Non motor symptoms (NMS) in idiopathic Parkinson’s disease (PD) are well studied and has an effect on quality of life in PD. NMS in…Dyspnea in Parkinson’s disease: A biomarker of disease’s severity?
Objective: The aim of our study was to determine the prevalence of dyspnea in a monocentric cohort of 153 non-demented PD patients (mean age: 63.9…Substantia nigra hyperechogenicity is similarly enlarged in Gaucher and in GBA mutation carriers
Objective: Testing the role of glycolipid accumulation in the risk for Parkinson's disease. Background: Increased risk for Parkinson's disease is well known among carriers of…α-synuclein aggregation and propagation in marmoset brains deteriorates its motor function
Objective: To confirm that α-synuclein aggregation and propagation in marmoset brains deteriorates its motor function. Background: Recently, the α-synuclein amyloid fibril is thought to be…GBA haploinsufficiency accelerated alpha synuclein pathology with altered lipid metabolism in a premotor model of Parkinson’s disease
Objective: To make Parkinson’s disease (PD) mice model and investigate the mechanism how glucocerebrosidase (gba) heterozygous mutations contribute to asyn pathology and development of PD.…Catecholamines interrelation in plasma of early diagnosed treatment-naive patients with Parkinson disease
Objective: To investigate the interrelation of catecholamines in the blood plasma of healthy people and PD patients. Background: The study “START-1” was funded by Investment…A patient with myotonic dystrophy type 1 and parkinsonism
Objective: We report the first case of myotonic dystrophy (DM) type 1 with DMPK mutations presenting with parkinsonian syndrome. Background: DM type 1 is a…