Ocular motor function in stiff person syndrome – Role of GABA and beyond
Objective: Delineate pathophysiology of gaze-holding function in stiff person syndrome (SPS). Background: Glutamic acid decarboxylase (GAD) catalyzes conversion of glutamate to gamma-aminobutyric acid (GABA). Anti-GAD…Peculiarities of Opsoclonus-Myoclonus Syndrome in India: A Systematic Review of reported cases
Objective: The aim of the study was to study the reported cases on opsoclonus-myoclonus syndrome in India and to analyze its peculiarities in comparison with…Does Niemann Pick Type C heterozygosity predispose to late-onset neurodegeneration?
Objective: Do single NPC1 or NPC2 mutation also predispose to late-onset neurodegeneration, e. g. PD or dementia? Background: Niemann-Pick type C (NPC) is an autosomal…Patient and Caregiver Experience With Pantothenate Kinase-Associated Neurodegeneration
Objective: To investigate the natural history of pantothenate kinase-associated neurodegeneration (PKAN) and the burden of illness. Background: PKAN is a rare autosomal recessive, progressive neurodegenerative…Corticomuscular and Intermuscular Coherence as a Biomarker of Pallidal Deep Brain Stimulation Efficacy in Dystonia
Objective: To find a biomarker of GPi-DBS efficacy in dystonia. Background: GPi-DBS has been proven effective and safe in medically refractory dystonia. However, the heterogeneity…Mirthful laughter avoided by directional stimulation in a Parkinson’s disease patient treated with deep brain stimulation
Objective: Show how directional steering stimulation can avoid non motor adverse effects in Parkinson disease patient underwent DBS. Background: Deep brain stimulation (DBS) has become…Single centre experiences of directional leads in Parkinson patients
Objective: To evaluate the use of segmented lead technology in clinical routine in patients undergoing subthalamic nucleus deep brain stimulation (STN-DBS). Background: Due to the…8-Contact Multiple Independent Current Control vs. 4-Contact Standard Deep Brain Stimulation of Subthalamus in Parkinson’s disease: a Double-blind Cross-over Trial
Objective: To explore the hypothesis that flexible stimulation (multiple independent current control over 8 contacts/hemisphere) is superior to standard stimulation (standard stimulation over 4 contacts)…Impact of electrode impedance changes in clinical outcomes of patients with Parkinson’s disease and subthalamic nucleus deep brain stimulation
Objective: To assess the longitudinal changes in impedance values of CV neurostimulation devices and its possible impact in the clinical outcome of PD patients with…Deep brain stimulation in Parkinson’s disease: From the stimulation of a nucleus to the stimulation of neuronal networks
Objective: To evaluate global changes in connectivity of large-scale structural brain networks in Parkinson's disease (PD) patients, and to test the hypothesis that deep brain…
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