Gaucher’s disease (GD) and Parkinsonism: An analysis from patients to relatives
Objective: To identify parkinsonian features in a cohort of GD patients and their relatives. Background: GD is a lysosomal storage disorder caused by GBA1 mutations…Novel population-specific mutationsin PINK1 and Parkin genes from India
Objective: To look for novel and population-specific genes for PD in 50 Indian families with Parkinson's disease Background: Till date, 138 mutations in PINK1 and…Loss of VPS29 disrupts retromer function and synaptic transmission, leading to neurodegeneration in Drosophila
Objective: To understand the role of the retromer complex in the central nervous system(CNS), and its link to Parkinson's disease (PD) susceptibility. Background: Mutations in…Prevalence of Autonomic dysfunction and its correlation with Clinico-imageological features in Parkinson’s Disease
Objective: To study the prevalence of autonomic dysfunction and to correlate with clinico-imageological features and to assess the impact of autonomic dysfunction on quality of…Association between peripheral inflammation and DATSCAN data of the striatal nuclei in different motor subtypes of Parkinson Disease
Objective: This work was designed to investigate peripheral inflammation in terms of Neutrophil-Lymphocyte ratio (NLR) concerning loss of dopaminergic uptake in caudate and putamen on…Diminished fMRI global signal differences between eyes closed and eyes open resting state in RBD and PD
Objective: test whether patients with Parkinson’s diseases (PD) and REM sleep behavior disorder (RBD) exhibit diminished state-related changes in their resting state fMRI global signal.…Long-term and dopamine dependent dynamics of subthalamic nucleus local field potentials in Parkinson’s disease
Objective: Using a new deep brain stimulation (DBS) pulse generator device that can record local field potentials (Activa PC+S, Medtronic Inc.), the current experiment investigated…Intrinsic functional connectivity correlates of anxiety in cognitively unimpaired drug-naïve patients with Parkinson’s disease
Objective: Using resting-state functional MRI, we investigated intrinsic brain networks connectivity correlates of anxiety symptoms in a cohort of cognitively unimpaired drug-naïve patients with Parkinson's…Gender-specific pattern of sensori-motor network connectivity in early untreated Parkinson’s disease patients
Objective: To investigate the presence of a disease-related gender effect on the spontaneous neuronal activity within the sensori-motor network (SMN) in early untreated Parkinson's disease…Brain network activation (BNA): A new biomarker for Parkinson’s disease?
Objective: We aimed to assess the ability of the Brain Network Activation (BNA) EEG analysis algorithm to differentiate between early-stage Parkinson’s disease (PD) patients and…
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